Sylvia Mechsner
ORCID: 0000-0002-1095-0048
· 211 papers in corpus
other
2017
BACKGROUND: Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation…
other
2017
To identify factors influencing the differential pain pathogenesis in peritoneal endometriosis (pEM) and peritoneal carcinomatosis in ovarian cancer (pOC), we undertook an experimental study. Tissue samples of 18 patients with pEM, 15 patie…
2016
The selected endometriosis tissue required the presence of glandular epithelial cells and stromal cells. ROI were developed by selecting â customâ mode applied to separate lumen, epithelial gland tissue and stromal tissue. The lumen ROI was…
2016
Setting parameter for nuclei size. The nucleus size was determined as depicted in Fig. 4a. It was based on blue color detection (hematoxylin staining). Brown color expressed by cell was restricted from interior radius −4,81 μm to exterior r…
2016
Manual counting of nerve fibers. Region of interests were selected randomly and marked with a border to obtain an area of 1Â mm2 each. A single nerve fiber was marked manually by using a tool available in HistoquestÂŽ software. (JPG 565Â kb…
case-report
2016
Establishing the diagnostic and surgical management of the inguinal Endometriosis, with further investigation of the biological character.The imaging findings of CT and PET-CT, biopsy, ultrasound, open surgery of the inguinal region with in…
observational
2016
OBJECTIVE: To identify and characterize endometriosis-associated immune cell infiltrates (EMaICI). Furthermore, to define occurrence and size of EMaICI in various types of endometriosis. METHODS: Immune cells were characterized in samples …
review
2016
Endometriosis is a chronic disease of women during their reproductive age. The most typical symptoms are dysmenorrhoea, dyspareunia, dysuria, cyclical and acyclical pelvic pain, bleeding disorders and infertility. These symptoms lead to sig…
2016
review
2016
Die Endometriose als klassische östrogenabhängige Erkrankung hat eine Reihe von Überlebensstrategien entwickelt, die es den ektopen Läsionen ermöglichen, sich zu entwickeln. Als wichtigste Pathogenesefaktoren gelten die von ovariellen Stero…
other
2016
STUDY OBJECTIVE: To evaluate the feasibility of a novel laparoscopic procedure for complete eradication of diaphragmatic endometriosis (DE). DESIGN: A retrospective multicenter study (Canadian Task Force Classification II-2). SETTING: Uni…
other
2016
BACKGROUND: The roles of the neurotrophins NGF (Neurotrophic growth factor) and BDNF (brain-derived neurotrophic factor) in neuronal growth and development are already known. Meanwhile, the neurotrophin receptors TrkA (tropomyosin related k…
nonrandomized-trial
2016
Introduction: Pelvic pain is a common problem in gynaecological practice. It is often unclear whether definite causality exists between reported symptoms and objective clinical findings of the female genital tract, and medical or operative …
observational
2016
STUDY HYPOTHESIS: Loss of protein BAF250a (ARID1A) expression is present in women with rectovaginal deep-infiltrating endometriosis (DIE) and endometriosis affecting the pelvic sentinel lymph nodes (PSLN). STUDY FINDING: Partial loss of pr…
other
2016
Endometriosis is a chronic inflammatory disease and one of the most common causes of pelvic pain. The mechanisms underlying pain emergence or chronic inflammation during endometriosis remain unknown. Several chronic inflammatory diseases in…
nonrandomized-trial
2015
Chemokines have been associated with endometriosis. Our study was aimed at evaluating the levels of six chemokines--CXCL8 (IL-8), CXCL12 (SDF-1), CCL2 (MCP-1), CCL5 (RANTES), CCL19 (MIP-3β), and CCL21 (6-Ckine)--in the peritoneal fluid (PF)…
2015
Immer wieder tritt bei Frauen nach laparoskopisch assistierter supracervikaler Hysterektomie (LASH) eine rektovaginale Endometriose auf, die operativ behandelt werden muss. Das Anliegen dieser Studie war es Patientinnen mit rektovaginaler E…
2015
Endometriose ist eine Östrogenabhängige inflammatorische Erkrankung und eine der häufigsten Ursachen für Unterbauchschmerzen. Die genaue Pathogenese der Erkrankung sowie die Ursachen der Schmerzentstehung sind bislang noch ungeklärt. Neuere…
2015
Endometriose, die zweithäufigste benigne gynäkologische Erkrankung, ist assoziiert mit chronischen Unterbauchschmerzen, Dysmenorrhoe, Dyspareunie und Dyschezie. Trotz der meist im Vordergrund stehenden Schmerzsymptomatik sind die Schmerzmec…
2015
2015
Die peritoneale Endometriose (pEM) und die Peritonealkarzinose des Ovarialkarzinoms (pOC) sind als Pathologien des Peritoneums mit sekundärer Absiedlung von gynäkologischer Bedeutung.
lab-animal
2015
Endometriosis occurs in approximately 10% of women and is associated with persistent pelvic pain. It is defined by the presence of endometrial tissue (lesions) outside the uterus, most commonly on the peritoneum. Peripheral neuroinflammatio…
observational
2015
Endometriosis is a prevalent benign disease, despite sharing several similarities with malignancies, such as the possibility of lymphatic spread. In malignancies, chemokines play a sovereign role in the process of metastasis. Metastasis-rel…
observational
2015
Bei Endometriose finden sich Endometrium-ähnliche Herde im Bauchraum, die auf den ovariellen Hormonzyklus reagieren. Es ist eine Erkrankung, die mit zyklischen und azyklischen Unterbauchschmerzen einhergeht. Die leitliniengerechte Therapie …
2015
Adenomyose uteri (AM) wird durch das Vorkommen von ektopen endometrialen Drüsen und Stromazellen im Myometrium charakterisiert. Als aktuelles Pathogenese Konzept der AM wird die „Tissue Injury And Repair (TIAR)“ Theorie diskutiert. Sie besa…