Kunihiro Okamura

No ORCID on file · 18 papers in corpus
2013

BACKGROUND: Recent studies have indicated new physiological roles for erythropoietin (Epo) unrelated to erythropoiesis. We previously demonstrated that the Epo concentrations in peritoneal ¯uid from patients with stage I endometriosis were …

lab-animal 2008
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.09.001

OBJECTIVE: To evaluate the effect of photodynamic therapy with aminolevulinic acid (ALA) on human adenomyosis xenografts in a mouse model. DESIGN: Human adenomyosis tissues were implanted SC into nude mice. We measured 5-aminolevulinic aci…

case-report 2007
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/j.1447-0756.2007.00503.x

Endometriotic nodules in the lower genital tract often cause dysmenorrhea and dyspareunia. We report here a case of posterior vaginal fornix endometriosis that was overlooked for several years. We performed a trans-vaginal resection after t…

other 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.01.057

OBJECTIVE: To investigate the effects of a selective cyclooxygenase (COX)-2 inhibitor on endometriosis xenografts in immunodeficient mice. DESIGN: Prospective placebo-controlled study. SETTING: An academic facility at a Japanese universit…

lab-animal 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.066

OBJECTIVE: To evaluate the potential of photodynamic therapy with aminolevulinic acid (ALA) on human adenomyosis-derived cells compared with endometrial stromal cells. DESIGN: In vitro study. SETTING: Department of Obstetrics and Gynecolo…

review 2006
The Tohoku Journal of Experimental Medicine ·doi:10.1620/tjem.210.175

Endometriosis is a condition characterized by ectopic endometrial tissues located outside of the uterus, most commonly found on the pelvic peritoneum or ovary. Endometriosis, which occurs in 7-10% of women in the general population and 71-8…

observational 2004
Fertility and sterility ·doi:10.1016/j.fertnstert.2004.03.059

OBJECTIVE: To identify any relationship between cyclooxygenase-2 expression and the intensity of severe, endometriosis-related dysmenorrhea. DESIGN: Prospective study. SETTING: University hospital. PATIENT(S): Patients with deep endometr…

other 2004
Fertility and sterility ·doi:10.1016/j.fertnstert.2004.07.946

OBJECTIVE: To evaluate Cox-2 inhibition on surgically induced endometriosis in rats. DESIGN: Prospective, randomized study SETTING: Academic facility. ANIMAL(S): Seventy adult female Sprague-Dawley rats. INTERVENTION(S): Uterine fragmen…

other 2003
Fertility and sterility ·doi:10.1016/s0015-0282(03)01181-6

OBJECTIVE: To investigate the clonality of ectopic gland cells in peritoneal endometriosis. DESIGN: Prospective study. University hospital. PATIENT(S): Seventeen women with surgically diagnosed endometriosis. INTERVENTION(S): Samples of …

2003
other 2003
Human Reproduction ·doi:10.1093/humrep/deg007

BACKGROUND: Recent studies have indicated new physiological roles for erythropoietin (Epo) unrelated to erythropoiesis. We previously demonstrated that the Epo concentrations in peritoneal fluid from patients with stage I endometriosis were…

lab-animal 2003
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2003.00104.x

PROBLEM: We sought to examine the role of Hsp60, a 60-kDa stress-responsive protein (hsp60) with potent immunostimulatory properties, in the pathophysiology of endometriosis. We investigated the response of peritoneal fluid mononuclear cell…

observational 2002
Gynecologic and obstetric investigation ·doi:10.1159/000049421

To estimate the probability of pregnancy in infertile women with endometriosis, two series of multivariate analyses were performed in Tohoku University Hospital. In the first series, from 1993 to 1997, 103 patients participated. The Cox pro…

other 2001
Fertility and sterility ·doi:10.1016/s0015-0282(01)01783-6

OBJECTIVE: To quantify and compare messenger RNA (mRNA) levels of ER-alpha and ER-beta among ovarian endometriotic cysts and red and black peritoneal endometriotic lesions. DESIGN: Prospective study. SETTING: University hospital. PATIENT…

observational 2001
Fertility and sterility ·doi:10.1016/s0015-0282(01)01752-6

OBJECTIVE: This study was undertaken to evaluate the immunohistochemical expression of the cell cycle inhibitor p27Kip1 and proliferation marker Ki67 in peritoneal endometriosis and eutopic endometrium. DESIGN: Prospective study. SETTING:…

case-report 2001
The Journal of the American Association of Gynecologic Laparoscopists ·doi:10.1016/s1074-3804(05)60628-7

A 21-year-old-woman had a double uterus with noncommunicating right uterine horn and communicating left uterine horn. The pelvic cavity showed evidence of endometriosis and adhesions from previous laparotomy. A finger was inserted under lap…

other 2001
Fertility and sterility ·doi:10.1016/s0015-0282(01)02003-9

OBJECTIVE: To investigate the angiogenic status of the vasculature in peritoneal endometriosis based on macroscopic appearance. DESIGN: Prospective study. SETTING: University hospital. PATIENT(S): Patients with peritoneal endometriosis. …

other 2000
Fertility and sterility ·doi:10.1016/s0015-0282(00)00712-3

OBJECTIVE: To quantify messenger RNA (mRNA) levels of the two estrogen receptor isoforms, estrogen receptor-alpha (ER-alpha) and estrogen receptor-beta (ER-beta) in the eutopic endometrium and ovarian endometriotic cysts. DESIGN: Prospecti…