Pietro Litta

OBJECTIVE: To delineate the panel of expression of phosphoinositide-specific phospholipase C (PI-PLC) signaling enzymes in normal endometrium and in endometriosis. DESIGN: Clinical/experimental study. SETTING: University. PATIENT(S): Hea…

This randomized, double blind, placebo-controlled study compared the usefulness of danazol 400mg vaginally versus 600mg orally in women as a preoperative preparation for hysteroscopic surgery. Ninety-one fertile women were randomly allocate…

STUDY OBJECTIVE: To estimate the efficacy and tolerability of low dose spinal anesthesia during operative hysteroscopy in a group of patients with high surgical risks. DESIGN: Case series study (Canadian Task Force Classification II-2). S…

To assess the most accurate diagnostic tool in diagnosing deep infiltrating endometriosis (DIE). A longitudinal prospective study between May 2005 and January 2011, in which 54 women suspected to have DIE on the basis of clinical symptoms, …

Purpose: To verify if different endometrial lesions determine the diagnostic symptom panel for a specific symptom. Methods: We recruited 537 women with endometriosis who underwent laparoscopic surgery. Data on patient characteristics, sever…

Purpose To verify if different endometrial lesions determine the diagnostic symptom panel for a specific symptom. Methods We recruited 537 women with endometriosis who underwent laparoscopic surgery. Data on patient characteristics, severit…

Purposeto determine the efficacy of laparoscopic excision of deep pelvic endometriosis (DPE).MethodsOne hundred and two highly symptomatic women with DPE underwent clinical examination, transvagina...

Purpose to determine the efficacy of laparoscopic excision of deep pelvic endometriosis (DPE). Methods One hundred and two highly symptomatic women with DPE underwent clinical examination, transvaginal ultrasound, nuclear magnetic resonance…

Endometrial curettings from a cohort of 24 women with endometriosis were compared with matched biopsies from 14 healthy, fertile women and examined for ultrastructural changes and the secretion of glycans bound by the lectin from Dolichos b…

Growing evidence is demonstrating that several peptides (corticotrophin-releasing factor, urocortins, ghrelin), proteins (leptin, adiponectin) and growth factors (vascular endothelial growth factor...

Growing evidence is demonstrating that several peptides (corticotrophin-releasing factor, urocortins, ghrelin), proteins (leptin, adiponectin) and growth factors (vascular endothelial growth factor; epidermal growth factor family of growth …

to compare the diagnostic accuracy of sonovaginography and NMR in the diagnosis of recto-vaginal endometriosis. alongitudinal prospective study in which women with recto-vaginal endometriosis suspected with medical history and/or pelvic exa…

Examination of 12 paired peritoneal ectopic and eutopic endometria for histochemical binding of Dolichos biflorus agglutinin, normally found in the mid-late secretory part of the cycle, showed a failure of lectin binding in 9 of 11 secretor…

Previously we showed that sonovaginography is an accurate ultrasonographic tool in the assessment of recto-vaginal endometriosis. The aim of this study was to compare the diagnostic accuracy of sonovaginography in the diagnosis of recto-vag…

Following a study in a baboon model of endometriosis, we here describe the morphology of ectopic peritoneal lesions in the human to examine the effects of an ectopic site on glandular structure and function. Ectopic biopsies from 17 women w…

Previously we showed that sonovaginography is an accurate ultrasonographic tool in the assessment of rectovaginal endometriosis. The aim of this study was to compare the diagnostic accuracy of sonovaginography and NMR in the diagnosis of re…

The recurrence of endometriosis varies from 6% to 10% and, among the non-gynaecological sites, the bowel is involved in 12%-37%. Various symptoms, such as dysmenorrhea, dyspareunia, chronic pelvic pain, diarrhoea, constipation, cyclic recta…