[Controlled ovarian stimulation protocols in endometriosis patients: with antagonist or agonist?]

Ya Yu, Kai Wei, Qiuping Yao, Shen Tian, Tian Shen, Kun Liang, Liming Zhou, Liping Wang, Min Jin
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2019 · vol. 48(2) , pp. 165–173 · doi:10.3785/j.issn.1008-9292.2019.04.07 · PMID:31309754 · PMC8800656 · W2973657383
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Abstract

OBJECTIVE: fertilization-embryo transfer (IVF-ET) in patients with endometriosis using antagonist protocol, long agonist protocol or prolonged agonist protocol. METHODS: Totally 313 patients with endometriosis were recruited in Reproductive Centers of the Second Affiliated Hospital of Zhejiang University School of Medicine,Jiaxing Women and Children's Hospital,and Ningbo Women and Children's Hospital from April 2017 to October 2018, including 81 patients treated with antagonist protocol (antagonist group), 148 treated with long agonist protocol (long agonist group) and 84 treated with prolonged agonist protocol (prolonged agonist group). The clinical and laboratory data of the patients were retrospectively analyzed to investigate the effect of ovarian stimulation protocols on the IVF-ET outcomes of patients with endometriosis. RESULTS: <0.05). CONCLUSIONS: Patients with endometriosis who used the antagonist protocol in IVF procedure could reduce the cost and time of Gn treatment, when combined with frozen-embryo transfer strategy the antagonist protocol has comparable clinical pregnancy outcome with long or prolonged agonist protocol, especially in those with diminished ovarian reserve, the higher available embryo rate can be achieved.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Ovulation Induction Ovulation Induction Embryo Transfer Female Fertilization in Vitro Humans Pregnancy Retrospective Studies

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