Long-Term Use of the Low Dose LHRH Analogue Combined With Monthly Medroxy-Progesterone Administration

A Lemay, Dodin Dewailly, S Dodin Dewailly
Hormone research · 1989 · vol. 32(1) , pp. 141–145 · doi:10.1159/000181330 · PMID:2515146 · W2036430860
article OA: closed CC0 ⤵ 5 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Low-dose buserelin and monthly medroxy-progesterone effectively treated endometriosis-related pelvic pain and uterine bleeding with few side effects, though minor bone demineralization may occur.

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Abstract

In a pilot study, chronic pelvic pain associated with endometriosis, dysmenorrhoea or menorrhagia has been treated for prolonged periods with low dose buserelin (daily) and medroxy-progesterone (monthly). The partial inhibition of ovarian function was effective in relieving pain and controlling uterine bleeding, with few side effects. There was no change in serum cholesterol level. A possible small bone demineralisation effect has been observed.

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Condition tags

dysmenorrheaendometriosischronic_pelvic_pain

MeSH descriptors

Buserelin Dysmenorrhea Endometriosis Medroxyprogesterone Menorrhagia Adult Buserelin Buserelin Drug Therapy, Combination Dysmenorrhea Endometriosis Female Humans Medroxyprogesterone Medroxyprogesterone Menorrhagia

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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License: CC0 · commercial use OK