Long-term use of the low dose LHRH analogue combined with monthly medroxy-progesterone administration
Non-randomised trial
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⤵ 5 in-corpus citations
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Low-dose buserelin and monthly medroxy-progesterone effectively treated endometriosis-related pelvic pain and uterine bleeding with few side effects, though minor bone demineralization may occur.
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Abstract
In a pilot study, chronic pelvic pain associated with endometriosis, dysmenorrhoea or menorrhagia has been treated for prolonged periods with low dose buserelin (daily) and medroxy-progesterone (monthly). The partial inhibition of ovarian function was effective in relieving pain and controlling uterine bleeding, with few side effects. There was no change in serum cholesterol level. A possible small bone demineralisation effect has been observed.
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Too few in-corpus citations on either side for a chart; here are the lists.
Cited by (4)
- Progestins for symptomatic endometriosis: a critical analysis of the evidence 1997
- Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study. Lupron Add-Back Study Group 1998
- Endometriosis: An Enigmatic Disease 1996
- Gonadotropin-releasing hormone agonist and estrogen-progestogen replacement therapy 1991
Cited by (4)
- Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study. Lupron Add-Back Study Group 1998
- Progestins for symptomatic endometriosis: a critical analysis of the evidence 1997
- Endometriosis: An Enigmatic Disease 1996
- Gonadotropin-releasing hormone agonist and estrogen-progestogen replacement therapy 1991
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- europepmc
- last seen: 2026-10-14T06:08:39.101224+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:14:10.100512+00:00
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