Long‐lasting analgesic effect of transcranial direct current stimulation in treatment of chronic endometriosis pain
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Transcranial direct current stimulation applied over the left primary motor cortex reduced chronic endometriosis pain by 60% acutely, with a 30% decrease sustained at four months.
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Abstract
Approximately 10-20% of women of reproductive age suffer from endometriosis, with 70-90% of these women reporting chronic pain symptoms that persist during their menstrual cycle. We are presenting a case in which a novel form of noninvasive brain stimulation called transcranial direct current stimulation was used as an intervention in a 32-year-old woman with persistent, chronic pain symptoms caused by endometriosis for 20 years. Ten daily, 20-min sessions of 2-mA anodal transcranial direct current stimulation were applied over the left primary motor cortex. Acutely, visual analog scale pain symptoms were reduced by 60%. There were also significant decreases in modules of the Endometriosis Health Profile. At the 4-month follow-up, the patient still expressed an overall decrease in pain symptoms of 30%.
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Cited by (4)
- Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment 2019
- Systematic review of quality of life measures in patients with endometriosis 2019
- Factors associated with ovarian endometriosis malignancy and its recurrence in Chinese women 2019
- Effect of one session of tDCS on the severity of pain in women with chronic pelvic pain 2017
Source provenance
- europepmc
- last seen: 2026-06-12T06:13:51.797165+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:39.907309+00:00
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