Long‐lasting analgesic effect of transcranial direct current stimulation in treatment of chronic endometriosis pain

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AI-generated summary by claude@2026-06, 2026-06-07

Transcranial direct current stimulation applied over the left primary motor cortex reduced chronic endometriosis pain by 60% acutely, with a 30% decrease sustained at four months.

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Abstract

Approximately 10-20% of women of reproductive age suffer from endometriosis, with 70-90% of these women reporting chronic pain symptoms that persist during their menstrual cycle. We are presenting a case in which a novel form of noninvasive brain stimulation called transcranial direct current stimulation was used as an intervention in a 32-year-old woman with persistent, chronic pain symptoms caused by endometriosis for 20 years. Ten daily, 20-min sessions of 2-mA anodal transcranial direct current stimulation were applied over the left primary motor cortex. Acutely, visual analog scale pain symptoms were reduced by 60%. There were also significant decreases in modules of the Endometriosis Health Profile. At the 4-month follow-up, the patient still expressed an overall decrease in pain symptoms of 30%.

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Outcome instruments

EHP-30

Condition tags

endometriosis

MeSH descriptors

Chronic Pain Endometriosis Transcranial Direct Current Stimulation Adult Chronic Pain Endometriosis Endometriosis Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

Cited by (4)

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europepmc
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