Menstruation-related disseminated intravascular coagulation in an adenomyosis patient: case report and review of the literature

Alice Cernogoraz, Luigi Schiraldi, Schiraldi L, Deborah Bonazza, Giuseppe Ricci
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2018 · vol. 35(1) , pp. 32–35 · doi:10.1080/09513590.2018.1488956 · PMID:30044152 · W2884231455
Review OA: closed CC0 ⤵ 5 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This case report describes a patient with adenomyosis who developed acute disseminated intravascular coagulation and subsequent kidney failure, successfully treated with hysterectomy, highlighting adenomyosis as a potential DIC cause.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Disseminated intravascular coagulation (DIC) is a high mortality coagulopathy that leads to simultaneous thrombotic and bleeding problems. It occurs as a complication in different disease as malignancies, obstetrical catastrophes, bacterial sepsis and traumas. We report on an extremely rare case of acute DIC in a patient with misdiagnosed adenomyosis and massive methrorragia which led to acute kidney failure. The patient was successfully treated with hysterectomy and blood product transfusions; however, a slight reduction of renal function persisted. We were able to confirm the cause-consequence link between adenomyosis and consumptive DIC since we saw the thrombi in the adenomyotic uterus from early hysterectomy specimen. Moreover, this is the first case, for the best of our knowledge, in which systemic consequences persist in an adenomyosis patient who developed a DIC. Early diagnose and treatment of acute DIC is essential for patient's survival and to prevent severe complications: adenomyosis should be kept in mind as a possible cause of DIC when a patient shows up with massive bleeding.

My notes (saved in your browser only)

Condition tags

adenomyosis

MeSH descriptors

Acute Kidney Injury Adenomyosis Disseminated Intravascular Coagulation Menstruation Disturbances Acute Kidney Injury Acute Kidney Injury Adenomyosis Adenomyosis Disseminated Intravascular Coagulation Disseminated Intravascular Coagulation Female Female Humans Humans Menstruation Disturbances Menstruation Disturbances Middle Aged Middle Aged

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (10)

Cited by (5)

Source provenance

europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:22:34.444095+00:00
License: CC0 · commercial use OK