Menstruation-related disseminated intravascular coagulation in an adenomyosis patient: case report and review of the literature

Alice Cernogoraz, Luigi Schiraldi, Deborah Bonazza, Giuseppe Ricci
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2018 · vol. 35(1) , pp. 32–35 · doi:10.1080/09513590.2018.1488956 · PMID:30044152 · W2884231455
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes a patient with adenomyosis who developed acute disseminated intravascular coagulation and subsequent kidney failure, successfully treated with hysterectomy, highlighting adenomyosis as a potential DIC cause.

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Abstract

Disseminated intravascular coagulation (DIC) is a high mortality coagulopathy that leads to simultaneous thrombotic and bleeding problems. It occurs as a complication in different disease as malignancies, obstetrical catastrophes, bacterial sepsis and traumas. We report on an extremely rare case of acute DIC in a patient with misdiagnosed adenomyosis and massive methrorragia which led to acute kidney failure. The patient was successfully treated with hysterectomy and blood product transfusions; however, a slight reduction of renal function persisted. We were able to confirm the cause-consequence link between adenomyosis and consumptive DIC since we saw the thrombi in the adenomyotic uterus from early hysterectomy specimen. Moreover, this is the first case, for the best of our knowledge, in which systemic consequences persist in an adenomyosis patient who developed a DIC. Early diagnose and treatment of acute DIC is essential for patient's survival and to prevent severe complications: adenomyosis should be kept in mind as a possible cause of DIC when a patient shows up with massive bleeding.

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Condition tags

adenomyosis

MeSH descriptors

Acute Kidney Injury Adenomyosis Disseminated Intravascular Coagulation Menstruation Disturbances Acute Kidney Injury Adenomyosis Disseminated Intravascular Coagulation Female Humans Menstruation Disturbances Middle Aged

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (10)

Cited by (5)

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