A Bicornuate Uterus With a Unilateral Cornual Adenomyosis

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AI-generated summary by gemini-2.5-flash-lite, 2026-06-07

This case study describes unilateral adenomyosis in the left uterine horn of a bicornuate uterus, supporting theories that pregnancy or acquired factors may contribute to adenomyosis development.

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AI-generated deep summary by qwen3.7-flash, 2026-08-15 · read from full text

This case report describes a 41-year-old woman with a bicornuate uterus who experienced intractable dysmenorrhea and subsequently underwent laparoscopically assisted vaginal hysterectomy. Pathological examination revealed that adenomyosis was confined to the left uterine myometrium, while the right cornua remained unaffected following a prior pregnancy in the left cavity. The authors conclude that this unilateral presentation supports theories linking pregnancy or other acquired factors to the pathogenesis of adenomyosis. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

BACKGROUND: Few reports have described adenomyosis in association with congenital uterine abnormalities. The authors present a case involving unilateral adenomyosis in a bicornuate uterus. CASE: A 41-year-old married gravida 1, para 1, first became aware that she had a double uterus 14 years earlier at her first prenatal examination when the gestation was identified in the left uterine cavity because of intractable dysmenorrhea. The patient underwent laparoscopically assisted vaginal hysterectomy. Pathological examination confirmed that adenomyosis had affected only the left uterine myometrium. CONCLUSION: The right uterine cornua of a bicornuate uterus served as the control after a pregnancy in the left cornua. The subsequent development of adenomyosis in the left cornua lends weight to theories that suggest pregnancy or other acquired factors may be involved in the pathogenesis and development of adenomyosis.
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Background

Few reports have described adenomyosis in association with congenital uterine abnormalities. The authors present a case involving unilateral adenomyosis in a bicornuate uterus. CASE: A 41-year-old married gravida 1, para 1, first became aware that she had a double uterus 14 years earlier at her first prenatal examination when the gestation was identified in the left uterine cavity because of intractable dysmenorrhea. The patient underwent laparoscopically assisted vaginal hysterectomy. Pathological examination confirmed that adenomyosis had affected only the left uterine myometrium.

Conclusion

The right uterine cornua of a bicornuate uterus served as the control after a pregnancy in the left cornua. The subsequent development of adenomyosis in the left cornua lends weight to theories that suggest pregnancy or other acquired factors may be involved in the pathogenesis and development of adenomyosis.

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Condition tags

dysmenorrheaadenomyosis

MeSH descriptors

Adenomyoma Congenital Abnormalities Hysterectomy, Vaginal Uterine Neoplasms Uterus Adenomyoma Adenomyoma Adult Biopsy, Needle Congenital Abnormalities Congenital Abnormalities Dysmenorrhea Dysmenorrhea Dysmenorrhea Female Follow-Up Studies Humans Hysterectomy, Vaginal Hysteroscopy Hysteroscopy

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Source provenance

europepmc
last seen: 2026-09-16T06:11:32.772430+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:15:41.664291+00:00
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