Pertubation with lidocaine--a non-hormonal, long-term treatment of dysmenorrhea due to endometriosis

Edelstam G, Greta Edelstam, Sjösten A, Anette Sjösten, Barbara Jablonowska, Jablonowska B, Svante Kjellberg, Kjellberg S, Spira J, Jack Spira
Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives · 2012 · vol. 3(2) , pp. 93–94 · doi:10.1016/j.srhc.2012.02.001 · PMID:22578757 · W1968133029
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Perturbation with lidocaine solutions in women with endometriosis significantly reduced dysmenorrhea over multiple cycles without complications.

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Abstract

The major symptoms of endometriosis are dysmenorrhea and infertility. Pertubations with lidocaine have been shown to reduce dysmenorrhea and have an enhancing effect on fertility. Different concentrations of lidocaine were evaluated in a randomized, double-blind study of pre-ovulatory pertubations with lidocaine solutions in women with dysmenorrhea. The patients had laparoscopically diagnosed endometriosis and normal fallopian tubes. Ninety pertubations were carried out without complications on 26 patients during up to six cycles. The effect was evaluated by means of questionnaires where a clinically significant reduction of dysmenorrhea was reported. Pertubation with lidocaine can be a non-hormonal treatment option for dysmenorrhea.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Anesthetics, Local Dysmenorrhea Lidocaine Adult Adult Anesthetics, Local Anesthetics, Local Dose-Response Relationship, Drug Dose-Response Relationship, Drug Double-Blind Method Double-Blind Method Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Endometriosis Female Female Humans

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (5)

Cited by (6)

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