Therapie mit Lokalanästhetika in Endokrinologie und Gynäkologie

Stefan Weinschenk
In: Gynäkologische Endokrinologie · 2022 · doi:10.1007/s10304-021-00428-0 · W4205959711
article OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-09 ⓘ

Treatment with local anesthetics is widely used for chronic pain, inflammation, functional, vegetative, and circulation disorders, with specific gynecological and endocrinological applications and rare severe side effects.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 ⓘ

The paper reviews the therapeutic use of local anesthetics in endocrinology and gynecology, outlining that although molecular mechanisms and pleiotropic effects are well described, controlled clinical studies are relatively few. It categorizes indications into chronic pain, chronic inflammation, functional and vegetative disorders, and circulation disorders, notes contraindications such as allergies and needle phobia, and mentions a common but harmless side effect of immediate circulatory weakness. In gynecology it identifies use cases including vulvodynia, chronic cystitis/colpitis, dysmenorrhea, unclear lower abdominal complaints, cyclic complaints, and scar pain, while in endocrinology it lists treatment-resistant endometriosis pain and climacteric complaints when hormone contraindications apply. This paper is centrally about endometriosis — it explicitly frames local anesthetic therapy as a non-hormonal option for treatment-resistant endometriosis pain.

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