Evaluation Of Mammographic Features In Women With Adenomyosis

Nezaket Kadıoğlu, Ayçağ YORGANCI, Harika GUMGUMCU, M. Kuntay KOKANALI, Şebnem Özyer, Yaprak ENGIN USTUN
In: Journal of Experimental and Clinical Medicine · 2022 · W4360593735
article OA: green CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Women with adenomyosis exhibited increased breast density, calcifications, and BIRADS classification, with adenomyosis being the sole predictor for BIRADS 3-4 categories.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This paper evaluated mammographic features in women diagnosed with adenomyosis, analyzing what imaging characteristics are present on mammography in this population. The study design and methods are described at a high level as an assessment of mammographic patterns associated with adenomyosis rather than a treatment or mechanistic investigation, with the main finding being the identified mammographic feature profile linked to adenomyosis. The abstract text provided does not include the paper’s specific results or any stated limitation, so the caveat is that the provided excerpt lacks explicit details on outcome magnitude and constraints. This paper is centrally about adenomyosis — it focuses on mammographic features in women with adenomyosis.

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Abstract

AbstractAim: This study aimed to investigate the mammographic features in women with adenomyosis to determine the relationship between adenomyosis and breast disease. Methods: In this study, the mammographic features of women with adenomyosis were recorded. For the control group, women who had mammography without any gynaecologic complaints and with normal pelvic ultrasound were selected. Results: The adenomyosis group had higher breast density, more micro and macro calcifications, and higher BIRADS-mammography classification than the control group. When patients with low mammographic density (Density A - B, n = 80) and high mammographic density (Density C - D, n = 60) were compared, there were no statistically significant differences between the groups except the presence of adenomyosis. When patients were compared according to the BIRADS 1 - 2 (n=114) and BIRADS 3 - 4 (n=26) category, age ≥ 49.5, gravidity ≥ 3, parity ≥ 2, and the presence of adenomyosis were significantly higher in the BIRADS 3 - 4 category. In the logistic regression analysis, the presence of adenomyosis was found to be the sole factor for BIRADS 3-4 category. Conclusion: The results of our study suggested that patients with adenomyosis have an increased risk of higher mammographic breast density and BIRADS 3 classification.
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- 1.Li X, Liu X, Guo SW.Clinical profiles of 710 premenopausal women with adenomyosis who underwent hysterectomy.J Obstet Gynaecol Res.2014;40(2):485-94. - 2.Szubert M, Kozirog E, et al.Adenomyosis and Infertility-Review of Medical and Surgical Approaches.Int J Environ Res Public Health.2021;18(3). - 3.Protopapas A, Grimbizis G, et al.Adenomyosis: Disease, uterine aging process leading to symptoms, or both?Facts Views Vis Obgyn.2020;12(2):91-104. - 4.Leyendecker G, Bilgicyildirim A, et al.Adenomyosis and endometriosis. Re-visiting their association and further insights into the mechanisms of auto-traumatisation.Arch Gynecol Obstet.2015;291(4):917-32. - 5.Donnez J, Donnez O, Dolmans MM.Uterine adenomyosis, another enigmatic disease of our time.Fertil Steril.2018;109(3):369-70. - 6.Bourdon M, Santulli P, et al.Immunological changes associated with adenomyosis: a systematic review.Hum Reprod Update.2021;27(1):108-29. - 7.Stratopoulou CA, Donnez J, Dolmans MM.Origin and Pathogenic Mechanisms of Uterine Adenomyosis: What Is Known So Far.Reprod Sci.2020. - 8.Grebic D, Gulic T, et al.The Role of Innate Immunity in the Pathogenesis of Breast Cancer.Breast Care (Basel).2021;16(1):1-5. Details Primary Language English Subjects Health Care Administration Journal Section Research Article Authors Ayçağ Yorgancı 0000-0003-2565-6789 Türkiye Harika Gümgümcü 0000-0003-0750-1353 Türkiye Şebnem Özyer 0000-0002-1326-4246 Türkiye Yaprak Üstün 0000-0002-1011-3848 Türkiye Publication Date October 29, 2022 Submission Date July 20, 2022 Acceptance Date August 5, 2022 Published in Issue Year 2022 Volume: 39 Number: 4

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