Clinical analysis of high-intensity focussed ultrasound ablation for abdominal wall endometriosis: a 4-year experience at a specialty gynecological institution

Zhang Xiao-Ying, Hua Duan, Duan Hua, Jinjuan Wang, Wang Jin-Juan, Guo Ying-Shu, Cheng Jiu-Mei, Jiumei Cheng, Hong Ye, Ye Hong, Chunyi Zang, Zang Chun-Yi
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2018 · vol. 36(1) , pp. 87–94 · doi:10.1080/02656736.2018.1534276 · PMID:30428731 · W2901695007
article OA: hybrid CC0 ⤵ 26 in-corpus citations
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This study analyzed 51 women treated with high-intensity focused ultrasound for abdominal wall endometriosis, finding a 3.9% recurrence rate and no severe complications over a 4-year follow-up.

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Abstract

Objective: To evaluate the long-term clinical effect of high-intensity focussed ultrasound (HIFU) as a non-invasive modality for ablation of abdominal wall endometriosis (AWE) foci.Methods: All women who were diagnosed with cutaneous endometriosis and underwent HIFU ablation and 4-year follow-up were included. Patient symptoms, imaging performed, HIFU ablation, recurrence, lesion location, size and number were collected and analyzed.Results: A total of 51 women with 57 painful abdominal wall masses with a median volume of 4.00 cm3 and a mean age of 30.5±2.12 years were treated with HIFU. The main symptoms were a palpable painful abdominal mass (93%), protrusion of the skin (28.1%, 16) or lack of protrusion of the skin (71.9%, 41). Ultrasound was initially performed in 100% (51) of women, whereas 6% (3) required MRI examinations to distinguish the features and range of the masses. Ablation was performed with a median 300 s of sonication time, 40 min treatment time, 150 W of power and 41800 J of total energy to treat lesions that were a median volume of 3.83 cm3. No severe complications occurred, except in one patient with a first-degree skin burn, during the 48-month follow-up period. The pooled recurrence of cutaneous endometriosis occurred in 3.9% (2) of women.Conclusion: The diagnosis of AWE should be confirmed with imaging of the lesion number, location, size and features before HIFU ablation. HIFU should be the first choice for the treatment of AWE as it is a non-invasive method, with high efficiency and safety and rapid postoperative recovery.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis High-Intensity Focused Ultrasound Ablation Adult Endometriosis Endometriosis Female High-Intensity Focused Ultrasound Ablation Humans Time Factors Young Adult

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