Hormonal and immunologic methods in the diagnosis and treatment of patients with benign ovarian tumors and endometriotic cysts

International journal of fertility · 1993 · vol. 38(2) , pp. 92–8 · PMID:8097504 · W2418948521
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This study evaluated hormonal and immunologic markers in patients with endometriotic cysts and benign ovarian tumors, finding elevated LH and abnormal receptor levels in endometriosis, suggesting hormone therapy for endometriotic cysts.

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Abstract

OBJECTIVE: To compare efficacy of various methods for characterizing endometriosis and benign ovarian tumors. DESIGN: Two parallel groups of patients, 54 with endometriotic ovarian cysts and 48 with benign tumors. SETTING: Central clinic. PATIENTS: Patients referred from all regions over a 5-year period. OUTCOME MEASURES: Estrogen Estrogen and progesterone receptor levels of endometrium and endometriotic foci, CA-125 concentration, and estradiol, progesterone, LH, and testosterone blood levels. RESULTS: LH levels elevated during follicular phase in patients; estradiol levels reduced; receptor levels abnormal in endometriosis, but not in benign ovarian cysts. CONCLUSIONS: Hormone therapy is adequate treatment for endometriotic cysts. CA-125 is not a reliable indicator for differential diagnosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Neoplasms Antigens, Tumor-Associated, Carbohydrate Antigens, Tumor-Associated, Carbohydrate Antigens, Tumor-Associated, Carbohydrate Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols Danazol Danazol Danazol Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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