Hormonal and immunologic methods in the diagnosis and treatment of patients with benign ovarian tumors and endometriotic cysts.

Adamyan L.V. Adamyan L, L V Adamyan, Fanchenko Nd, N D Fanchenko, Alexeyeva Ml, M L Alexeyeva, Andreyeva YeN, Novikov YeA, Israt Jahan, I Jahan
International journal of fertility · 1993 · vol. 38(2) , pp. 92–8 · PMID:8097504 · W2418948521
article OA: closed CC0 ⤵ 7 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study evaluated hormonal and immunologic markers in patients with endometriotic cysts and benign ovarian tumors, finding elevated LH and abnormal receptor levels in endometriosis, suggesting hormone therapy for endometriotic cysts.

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Abstract

OBJECTIVE: To compare efficacy of various methods for characterizing endometriosis and benign ovarian tumors. DESIGN: Two parallel groups of patients, 54 with endometriotic ovarian cysts and 48 with benign tumors. SETTING: Central clinic. PATIENTS: Patients referred from all regions over a 5-year period. OUTCOME MEASURES: Estrogen Estrogen and progesterone receptor levels of endometrium and endometriotic foci, CA-125 concentration, and estradiol, progesterone, LH, and testosterone blood levels. RESULTS: LH levels elevated during follicular phase in patients; estradiol levels reduced; receptor levels abnormal in endometriosis, but not in benign ovarian cysts. CONCLUSIONS: Hormone therapy is adequate treatment for endometriotic cysts. CA-125 is not a reliable indicator for differential diagnosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Ovarian Neoplasms Antigens, Tumor-Associated, Carbohydrate Antigens, Tumor-Associated, Carbohydrate Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols Danazol Danazol Diagnosis, Differential Endometriosis Endometriosis Endometriosis Endometrium Endometrium Female Follicle Stimulating Hormone Follicle Stimulating Hormone Gonadal Steroid Hormones Gonadal Steroid Hormones Humans

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