ROLE OF HYDROGEN PEROXIDE PRODUCTS AND THEIR IMMINENT ROLE IN PATIENTS WITH DEGENERATING ENDOMETRIOSIS

Muhammad Zeeshan Anwar, Khokhar Mas, Rashid Ms, Arif Malik, L Carvalho, M Abro, C Biscotti, R Sharma, B Nutter, T Falcone, I Sharma, L Dhaliwal, S Saha, S Sangwan, V Dhawan, R Rong, S Ramachandran, N Santanam, A Murphy, S Parthasarathy, J Fujii, Y Iuchi, F Okada, M Chandra, M Panchatcharam, S Miriyala, R Siddiqui, K Harvey, W Stillwell, G Mt, L Bernstein, A Trk, A Van Langendonckt, F Casanas-Roux, J Donnez, C Petean, R Ferriani, R Reis, M De Moura, A Jordao, P Navarro, M Gney, B Oral, N Karahan, T Mungan, J Mier-Cabrera, L Jimenez-Zamudio, E Garcia-Latorre, Hernandez-Guerrero C, H Ohkawa, N Ohishi, K Tagi, K Maxey, K Maddipati, J Birkmeir, J Salonen, M Valko, D Leibfritz, J Moncol, Mtd Cronin, M Mazur, J Telser, J Cracowskia, O Ormezzanob, A Agarwal, S Gupta, K Baboo, Z Chen, X Zhang, I Lambrinoudaki, A Augoulea, G Christodoulakos, E Economou, G Kaparos, A Kontoravdis, G Polak, I Wertel, B Barczyski, W Kwaniewski, W Bednarek, J Kotarski, M Hafeez, T Yasin, U Safdar, S Waquar, Rana Malik, A, R Khalil, Q Ali, A Malik, B Hameed, J Ali, A Siddique, A Fateh, N Idrees, M Rashid, M Kari, R Rashid, M Rana, A Amjad, M Omer, S Malik, M Anjum, A Riaz, R Ali, M Nadeem, Hafeez, Mm, A Khalid, U Daraaz, K Hussain, H Chudhary, A Amin, M Malik, S Ali, S Gillani, M Afzal, K Parveen
In: International Journal of Biology, Pharmacy and Allied Sciences · 2021 · vol. 10(2) · doi:10.31032/ijbpas/2021/10.2.5390b · W4206013080
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⚙ AI-generated summary by claude@2026-06, 2026-06-11 ⓘ

This study investigated lipid peroxidation biomarkers and DNA damage in women with advanced endometriosis, finding elevated levels associated with the condition.

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Abstract

Endometriosis is an inflammatory condition characterised by existence of endometrial tissue in extra uterine locations, being aggressive and invasive can cause a significant decrease in quality of life. Various scientific evidence suggests that peritoneal fluid of women suffering from endometriosis has elevated concentration of proinflammatory cytokines, reactive oxygen species as well as rich in low density lipoprotein which are able to upregulate the formation of oxidised lipid components in an inflammatory milieu along with increased number of active macrophages. Consequently formation of inflammatory response together with the existence of local oxidative environment possibly play an active role in the pathogenesis of endometriosis. It has been reported that lipidperoxidation end products are increased in serum of women with endometriosis. Current study was aimed to identify the levels of lipidperoxidation biomarkers in women diagnosed with advance stage of endometriosis in order to determine the status of lipidperoxidation as well as lipidperoxidation end product induced DNA damage in women with endometriosis.

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Condition tags

endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (36)

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