Benign gynecologic conditions associated with a CA-125 level > 1,000 U/mL. A case report.
Case report
OA: closed
CC0
⤵ 9 in-corpus citations
AI-generated summary
A high CA-125 level (>1,000 U/mL) in a patient with dysmenorrhea was associated with benign cystic adenomyosis and uterine endometriosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
CA-125 was initially investigated as a marker of ovarian cancer. However, various studies have noted that it can be minimally elevated in benign conditions.A case of CA-125 > 1,000 U/mL was associated with benign gynecologic conditions. A 37-year-old woman with a history of endometriosis and premature ovarian failure underwent hormonal therapy for donor in vitro fertilization. After an unsuccessful cycle, severe dysmenorrhea developed. Investigation revealed a CA-125 level of 1,036 U/mL and a uterine mass. On exploratory laparotomy, cystic adenomyosis and uterine endometriosis was found. After excision of these areas, the CA-125 levels returned to normal. In this case, cystic adenomyosis and endometriosis of the uterine serosa were responsible for the elevated CA-125 level.Very high levels of CA-125 are not always associated with a malignant process.
My notes (saved in your browser only)
Condition tags
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (8)
- Uterine adenomyotic cyst with markedly elevated serum CA19‑9 and CA125 levels: A case report 2022
- Extremely elevated serum CA125 and CA19-9 levels following the rupture of ovarian endometrioma: a case report 2012
- Adenomyosis With Extremely Elevated CA 125 Levels 2009
- [Physiopathologic, diagnostic and therapeutic evolution in the management of adenomyosis: review of the literature] 2004
- High level of CA 125 due to large endometrioma 2004
- Extremely elevated CA 125 level due to an unruptured large endometrioma 2003
- Ovarian cancer in a woman previously diagnosed with endometriosis and an extremely high serum CA-125 level 2001
- Extremely elevated serum CA125 due to endometriosis 1999
Source provenance
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
License: CC0
· commercial use OK