Rectal endometriosis mimicking primary rectal adenocarcinoma

Jingjing Hu, Mojgon Hosseini, Farnaz Hasteh, P. Murphy, Paul Murphy, Christopher Pare, Wilson T Kwong, Wilson Kwong, Charmi Patel
Diagnostic cytopathology · 2021 · vol. 49(12) , pp. E437–E442 · doi:10.1002/dc.24847 · PMID:34406702 · W3194208172
article OA: closed CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case study presents deep rectal endometriosis that mimicked primary rectal adenocarcinoma on cytology and MRI, highlighting characteristic cytologic features.

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Abstract

Endometriosis is a benign entity defined as the presence of endometrium tissue outside of uterine cavity. It is a common disease involving peritoneum, pelvic organs, gastrointestinal tract, and so on. Diagnosis based on cytology specimen can be challenge when we encounter increased cytological atypia in the glandular epithelium, with abundant inflammatory cells and debris in the background. We presented a case of deep rectal endometriosis mimicking rectal adenocarcinoma on cytology specimen and on MRI imaging studies. The combination of endometrial glands, cellular Mullerian stroma, hemorrhage, and hemosiderin-laden macrophages are the characteristic features on cytologic specimens.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Rectal Neoplasms Rectum Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Biopsy, Fine-Needle Diagnosis, Differential Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium Endosonography Female Humans Magnetic Resonance Imaging

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (34)

Cited by (3)

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europepmc
last seen: 2026-06-12T06:13:51.797165+00:00
openalex
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License: CC0 · commercial use OK