Long‐Term Danazol Treatment for an Adolescent Girl with Aplastic Anemia

Gen‐ichi Nakamura, G. Nakamura, Kiyotaka Yoshimitsu, Haruo Ootsuka, Hitoo Nakano, Yukihiro Nagata
In: Asia-Oceania Journal of Obstetrics and Gynaecology · 1986 · vol. 12(3) , pp. 365–370 · doi:10.1111/j.1447-0756.1986.tb00207.x · PMID:3778317 · W2120783852
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Long-term danazol treatment for four years and ten months suppressed uterine bleeding and normalized hematological findings in an adolescent girl with aplastic anemia, with minimal side effects.

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Abstract

Abstract Danazol was administered for four years and ten months to control uterine bleeding in a 12‐year‐old girl who had had aplastic anemia. During treatment, ovulation was suppressed and the amount of uterine bleeding was much less than that of the usual monthly periods. After 58 months of danazol therapy, all the hematological findings became normal. At present, despite restoration of the normal menstrual cycles, she has normal hematological values without blood transfusions. There were few side effects during the ingestion of danazol. Danazol seems to be effective for the long‐term control of uterine bleeding.

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