Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome

Langenberg PW, Patricia Langenberg, Patricia W Langenberg, Wallach EE, Edward E. Wallach, Daniel J. Clauw, Howard FM, Fred M. Howard, Christina M Diggs, Diggs CM, Christina Diggs, Ursula Wesselmann, Greenberg P, Patty Greenberg, Warren JW, John W. Warren
American journal of obstetrics and gynecology · 2009 · vol. 202(3) , pp. 286.e1–286.e6 · doi:10.1016/j.ajog.2009.10.866 · PMID:20022588 · W1980987467
Observational OA: closed CC0 ⤵ 2 in-corpus citations
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This paper examines the relationship between pelvic pain and surgical procedures performed on women prior to a diagnosis of interstitial cystitis/painful bladder syndrome.

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Abstract

OBJECTIVE: The objective of the study was to compare subjects with interstitial cystitis/painful bladder syndrome (IC/PBS) with controls on prior surgeries. STUDY DESIGN: IC/PBS subjects were compared with matched controls on surgeries and possible surgical indications prior to their index dates. RESULTS: Adjusted for demographic variables, logistic regression showed subjects exceeded controls in surgeries longer than 12 months and less than 1 month before the index date. However, addition of possible surgical indications showed chronic pelvic pain (CPP) to have a strong association with IC/PBS, whereas associations with surgeries were reduced to nonsignificance. CONCLUSION: Although women with IC/PBS were more likely to have experienced prior surgeries than controls, the apparent indications for surgeries, not the surgeries themselves, were stronger risk factors for IC/PBS. In particular, a prior history of CPP had a strong association with IC/PBS. Several features of study design, including extensive medical record review, suggest that prior CPP was not undiagnosed IC/PBS. Further investigation of CPP may yield insight into the pathogenesis of IC/PBS.

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Condition tags

endometriosischronic_pelvic_paininterstitial_cystitis

MeSH descriptors

Cystitis, Interstitial Gynecologic Surgical Procedures Pelvic Pain Urologic Surgical Procedures Adult Adult Case-Control Studies Case-Control Studies Cystitis, Interstitial Cystitis, Interstitial Endometriosis Endometriosis Endometriosis Fatigue Syndrome, Chronic Fatigue Syndrome, Chronic Fatigue Syndrome, Chronic Female Female Fibromyalgia Fibromyalgia

Citation neighborhood (2-hop)

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References (32)

Cited by (2)

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License: CC0 · commercial use OK