Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome

Langenberg PW, Patricia Langenberg, Patricia W Langenberg, Wallach EE, Edward E. Wallach, Daniel J. Clauw, Howard FM, Fred M. Howard, Christina M Diggs, Diggs CM, Christina Diggs, Ursula Wesselmann, Greenberg P, Patty Greenberg, Warren JW, John W. Warren
American journal of obstetrics and gynecology · 2009 · vol. 202(3) , pp. 286.e1–286.e6 · doi:10.1016/j.ajog.2009.10.866 · PMID:20022588 · W1980987467
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This paper examines the relationship between pelvic pain and surgical procedures performed on women prior to a diagnosis of interstitial cystitis/painful bladder syndrome.

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Abstract

ObjectiveThe objective of the study was to compare subjects with interstitial cystitis/painful bladder syndrome (IC/PBS) with controls on prior surgeries.Study designIC/PBS subjects were compared with matched controls on surgeries and possible surgical indications prior to their index dates.ResultsAdjusted for demographic variables, logistic regression showed subjects exceeded controls in surgeries longer than 12 months and less than 1 month before the index date. However, addition of possible surgical indications showed chronic pelvic pain (CPP) to have a strong association with IC/PBS, whereas associations with surgeries were reduced to nonsignificance.ConclusionAlthough women with IC/PBS were more likely to have experienced prior surgeries than controls, the apparent indications for surgeries, not the surgeries themselves, were stronger risk factors for IC/PBS. In particular, a prior history of CPP had a strong association with IC/PBS. Several features of study design, including extensive medical record review, suggest that prior CPP was not undiagnosed IC/PBS. Further investigation of CPP may yield insight into the pathogenesis of IC/PBS.

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Condition tags

endometriosischronic_pelvic_paininterstitial_cystitis

MeSH descriptors

Cystitis, Interstitial Gynecologic Surgical Procedures Pelvic Pain Urologic Surgical Procedures Adult Case-Control Studies Cystitis, Interstitial Endometriosis Endometriosis Fatigue Syndrome, Chronic Fatigue Syndrome, Chronic Female Fibromyalgia Fibromyalgia Gynecologic Surgical Procedures Humans Leiomyoma Leiomyoma Logistic Models Pelvic Pain

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