Isolated Appendiceal Endometriosis
Case report
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⤵ 11 in-corpus citations
AI-generated summary
This paper reviews cases of isolated appendiceal endometriosis, a rare condition where endometriosis is found only in the appendix, exploring its presentation and management.
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Abstract
BACKGROUND: Pain associated with appendiceal endometriosis can mimic other intra-abdominal pathology. The diagnosis is usually obvious during gross inspection of the appendix; however, the absence of classical macroscopic appearances may lead to missed cases in which the patient's pain is misdiagnosed and inappropriately managed.
CASE: A 34-year-old woman presented with cyclical right iliac fossa pain and an elevated serum C-reactive protein of 13 mg/L (normal < 5 mg/L). Diagnostic laparoscopy showed an isolated appendiceal mass with no pelvic endometriosis, and an appendectomy was performed. Histopathology demonstrated appendiceal endometriosis without macroscopic involvement of other pelvic organs.
CONCLUSION: This case gives insight into the pathophysiology of endometriosis. We advocate routine appendectomy in women with unexplained recurrent abdominal pain because a diagnostic laparoscopy may miss isolated endometriosis of the appendix, and we now have evidence that this may have no external features suggesting the diagnosis. Additionally, endometriosis can involve the gastrointestinal tract without involvement of the reproductive organs. This is important information in the further progression of theories underlying the pathophysiology of endometriosis.
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References (10)
- Appendiceal endometriosis presenting as perforated appendicitis: report of a case and review of the literature via openalex
- A reappraisal of the coelomic metaplasia theory by reviewing endometriosis occurring in unusual sites and instances via openalex
- Endometriosis at several sites, cyclic bowel symptoms, and the likelihood of the appendix being affected via openalex
- Endometriosis causing acute appendicitis complicated with hemoperitoneum via openalex
- Endometriosis: its association with retrograde menstruation, dysmenorrhoea and tubal pathology via openalex
- Endometriosis of the male urinary system: a case report via openalex
- Endometriosis of the vermiform appendix via openalex
- Endometriosis of the vermiform appendix; review of literature, with addition of nine new instances, one of which caused severe melena via openalex
- Intestinal endometriosis: presentation, investigation, and surgical management via openalex
- W6605984143 via openalex
Cited by (11)
- Imaging Findings in Symptomatic Appendiceal Endometriosis: A Systematic Review of Case Reports 2025
- Appendiceal Endometriosis: A Comprehensive Review of the Literature 2023
- Massive endometriosis mimicking tumor – unusual cause of appendiceal intussusception 2023
- Apendicitis aguda relacionado con endometriosis infiltrativa profunda: reporte de caso 2021
- Acute Appendicitis Secondary to Appendiceal Endometriosis 2020
- Peritoneovaginal Fistula and Appendicitis-Related Pelvic Abscess in Pregnancy 2020
- Emergency surgery for appendectomy and incidental diagnosis of superficial peritoneal endometriosis in fertile age women 2020
- Endometriosis of the duplex appendix: A case report and review of the literature 2019
- Isolated appendiceal endometriosis resulting in intussusception 2018
- Da vinci SILS-appendectomy for appendiceal endometriosis secondary to stage IV endometriosis: a case report and review of literature 2018
- Endometriosis of the appendix presenting as acute appendicitis with unusual appearance 2018
Source provenance
- europepmc
- last seen: 2026-10-15T06:08:49.021275+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:18:43.609252+00:00
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