Clinical Outcomes of Patients with High-Grade Ovarian Carcinoma Arising in Endometriosis Compared to Ovarian High-Grade Serous Carcinoma

İbrahim Yalçın, Hanifi Şahin, Mustafa Erkan Sarı, Nihan Haberal, Eda Adeviye Şahin, Hüsnü Çelik, Mehmet Mutlu Meydanlı, Ali̇ Ayhan
In: Indian Journal of Gynecologic Oncology · 2021 · vol. 19(4) · doi:10.1007/s40944-021-00559-z · W3185445595
article OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

High-grade ovarian carcinoma arising in endometriosis showed lower recurrence rates and better 5-year disease-free survival compared to high-grade serous carcinoma, though overall survival was similar.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This multicenter retrospective case–control study compared prognosis for high-grade ovarian carcinoma arising in endometriosis (OCAE) versus ovarian high-grade serous carcinoma (HGSC) in women treated at two gynecologic oncology centers in Turkey from 2006–2016. Seventy women with high-grade OCAE were included and matched by attributing each case to two women with ovarian HGSC, with recurrence and survival assessed using Kaplan–Meier methods. High-grade OCAE had a lower recurrent disease rate than HGSC (15.7% vs 33.6%, p = 0.008) and a higher 5-year disease-free survival (78.3% vs 56.2%, p = 0.007), while 5-year overall survival was not significantly different (79.5% vs 70.1%, p = 0.210). As a retrospective chart review, it is subject to limitations in design and potential selection or confounding. This paper is centrally about endometriosis — it specifically evaluates clinical outcomes of high-grade ovarian carcinoma arising in endometriosis compared with high-grade serous ovarian carcinoma.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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last seen: 2026-06-10T17:14:06.276822+00:00
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