Gonadotropin-releasing hormone analogs in the treatment of endometriomas
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This paper reviews the use of gonadotropin-releasing hormone analogs for treating endometriomas, exploring their efficacy and potential side effects.
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Abstract
A limited number of small studies have assessed the efficacy of gonadotropin-releasing hormone agonists in the treatment of ovarian endometriomas. Most of these trials have not used quantitative measurements to evaluate the effects of therapy on disease resolution. The results available thus far suggest that nafarelin, buserelin, and histrelin offer modest degrees of efficacy, similar to that of danazol, in the management of patients with ovarian endometriotic cysts. Gonadotropin-releasing hormone agonists appear to be most efficacious when endometriomas are less than 1 cm in size.
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References (8)
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- Treatment of endometriosis with a long-acting gonadotropin-releasing hormone agonist. via openalex
- Treatment of endometriosis with a potent agonist of gonadotropin-releasing hormone (nafarelin) via openalex
- W2415755045 via openalex
- W2416488540 via openalex
- W6607058909 via openalex
Cited by (20)
- Endometriosis 2021
- Endometriosis 2012
- An investigation of the surgical treatment of endometriosis 2010
- Endometriosis 2007
- Optimizing Gonadotropin-Releasing Hormone Agonist Therapy in Women with Endometriosis 2004
- Treatment of Ovarian Endometrioma 2003
- GnRH Analogues, Transvaginal Ultrasound-Guided Drainage and Intracystic Injection of Recombinant Interleukin-2 in the Treatment of Endometriosis 2003
- Controversias en el manejo quirúrgico del endometrioma ovárico 2002
- Use of intraperitoneal interferon α-2b therapy after conservative surgery for endometriosis and postoperative medical treatment with depot gonadotropin-releasing hormone analog: a randomized clinical trial 2002
- Deeply Infiltrating Endometriosis: Implications, Diagnosis, and Management 2001
- Postoperative administration of monophasic combined oral contraceptives after laparoscopic treatment of ovarian endometriomas: A prospective, randomized trial 2000
- Endometriosis 2000
- Reoperation after laparoscopic treatment of ovarian endometriomas by excision and by fenestration 1999
- Ultrasound guided aspiration of endometrioma — a new therapeutic modality to improve reproductive outcome 1999
- Laparoscopy versus microsurgery by laparotomy for excision of ovarian cysts in patients with moderate or severe endometriosis 1996
- Treatment of Ovarian Endometriosis 1995
- MANAGEMENT OF ENDOMETRIOSIS IN WOMEN OLDER THAN 40 YEARS OF AGE 1993
- Laser laparoscopy—indications, techniques and results 1993
- Ultrasound‐guided aspiration of ovarian endometriotic cysts 1993
- Treatment of estrogen-dependent gynecological disorders with the gonadotropin releasing hormone agonist buserelin 1991
Source provenance
- europepmc
- last seen: 2026-09-06T09:34:12.023084+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:12:10.587122+00:00
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