Danazol and benign intracranial hypertension.

Ajay M. Shah, Thomas A. Roberts, I N McQueen, Jill Graham, Kelcey Walker
In: BMJ · 1987 · vol. 294(6583) , pp. 1323 · doi:10.1136/bmj.294.6583.1323 · PMID:3109637 · PMC1246487 · W2020685069
article OA: bronze CC0 ⤵ 7 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report describes the successful use of exchange transfusion in a patient with amniotic fluid embolism, enabling rapid removal of harmful substances and replenishment of essential components.

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Abstract

10% of maternal deaths, and the reported mortality is as high as 80% in some series.2 Amniotic fluid embolism may occur after diagnostic amniocentesis, but this is uncommon. It is more likely to occur after hypertonic saline or dextrose is injected into the amniotic fluid.' In our patient exchange transfusion allowed rapid removal of red cell debris and haemoglobin from the circulation and provided red cells and clotting factors in fresh plasma.

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