Medical treatment of endometriosis
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⤵ 9 in-corpus citations
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This review outlines current medical treatments for endometriosis, focusing on hormonal suppression and targeted therapies, which moderately reduce pain but do not improve fertility.
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Abstract
The medical treatment of endometriosis is a critical aspect of the therapeutic approach to this disease. This review will present an overview of current literature about the medical treatment of endometriosis, without referring to the surgical treatment or a combination of both. The main purpose of the current medical treatment of endometriosis is to create an amenorrheic state, in other words, to create a hypoestrogenic environment by suppressing estrogen secretion of the ovary. Current research has focused upon medications designed to attack specific aspects of the development and maintenance of endometriosis. This includes progesterone receptor modulators, gonadotropin releasing hormone (GnRH) analogs, aromatase inhibitors and, tumor necrosis factor alpha (TNFalpha) inhibitors, angiogenesis inhibitors, matrix metalloproteinase inhibitors and estrogen receptor beta agonists like inmunomodulators. These drugs show decreased spreading of lesions and reduced disease related symptoms. Medical treatment is moderately effective in reducing pain but ineffective in improving fertility; a combination of medical treatment with assisted reproductive technology may be beneficial in improving fertility.
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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (9)
- Cesarean Section Scar Nodule, Ovarian Cyst, and Dysmenorrhea 2020
- The impact of infertility diagnosis on embryo-endometrial dialogue 2018
- Lipoxin A4 Suppresses Estrogen-Induced Epithelial-Mesenchymal Transition via ALXR-Dependent Manner in Endometriosis 2017
- Endometriosis, dysmenorrhoea and diet 2013
- Minimally invasive gynecologic procedures 2011
- Endometriosis, dysmenorrhea and diet--what is the evidence? 2007
- Influence of endometriosis on visceromotor and cardiovascular responses induced by vaginal distention in the rat 2007
- Investigating endometriosis: symptoms, diagnosis and treatment 2006
- Local application of danazol-loaded hyaluronic acid hydrogel to endometriosis in a rat model 2006
Source provenance
- europepmc
- last seen: 2026-10-14T06:08:39.101224+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:03:24.829172+00:00
License: CC0
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