[Serum and peritoneal fluid CA-125 concentration in women with endometriosis]

D Kraśnicki, Kraśnicki D
Ginekologia polska · 2001 · vol. 72(12A) , pp. 1365–9 · PMID:11883280 · W2399594092
Other OA: closed CC0 ⤵ 8 in-corpus citations
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Peritoneal fluid CA-125 levels were significantly higher than serum levels and elevated in women with endometriosis, suggesting its utility for detecting the disease, especially in early stages.

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Abstract

OBJECTIVE: To evaluate the clinical utility of CA-125 measurements in peritoneal fluid (PF) as an indicator of endometriosis. DESIGN: CA-125 levels in paired serum and peritoneal fluid were assessed by IMx CA-125 Assay (ABBOTT). PATIENTS: 107 women with and without endometriosis, undergoing laparoscopy during the luteal phase of the menstrual cycle were selected for the study. RESULTS: CA-125 levels in peritoneal fluid were higher than those found in serum and were significantly elevated (P < 0.05) in comparison to the control group. In women with endometriosis stage I-II and stage III-IV. CA-125 levels in serum were increased only in stage III-IV. CONCLUSIONS: The sensitivity of the peritoneal fluid CA-125 test for endometriosis is higher than the respective serum test. The measurement of CA-125 levels in PF could be useful in the detection of the early stage endometriosis, which seems to be missed by the CA-125 serum test.

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid CA-125 Antigen Endometriosis Adult Adult Ascitic Fluid Ascitic Fluid CA-125 Antigen CA-125 Antigen CA-125 Antigen Case-Control Studies Case-Control Studies Endometriosis Endometriosis Endometriosis Female Female Humans Humans Luteal Phase

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

Cited by (8)

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