Endometriosis. Un largo camino

P. Carrillo Torres, Maigualida Zamora, F. Carmona Herrera
In: Clínica e Investigación en Ginecología y Obstetricia · 2021 · vol. 48(4) , pp. 100686 · doi:10.1016/j.gine.2021.100686 · W3180413010
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This review discusses the hormone-dependent nature of endometriosis, its prevalence, changing diagnostic and treatment paradigms, and emerging understanding of its association with obstetric complications and comorbidities.

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Abstract

La endometriosis es una patología hormonodependiente causada por la presencia de tejido endometrial fuera de la cavidad uterina, que induce una reacción inflamatoria crónica. Tiene una prevalencia del 10% en mujeres en edad reproductiva, pudiendo alcanzar hasta el 50% entre mujeres con infertilidad. Es una enfermedad de interés creciente debido a su prevalencia y a los avances científicos ocurridos que han permitido conocer sus diferentes fenotipos, derivando en un diagnóstico más preciso y un tratamiento con un enfoque multidisciplinar. En los últimos años han cambiado muchos paradigmas en torno a esta patología, tanto en su etiopatogenia como en su diagnóstico y tratamiento. Además, han tomado interés creciente aspectos olvidados anteriormente, como su relación con las complicaciones obstétricas y sus comorbilidades asociadas. Tratamos su impacto a lo largo de la vida de las pacientes, haciendo énfasis en nuevas perspectivas que están revolucionado la manera de entender la endometriosis. Endometriosis is a hormone-dependent disease caused by the presence of endometrial tissue outside the uterine cavity, which induces a chronic inflammatory reaction. It has a prevalence of 10% in women of reproductive age and can reach up to 50% among women with infertility. It is a disease of growing interest due to its prevalence and to the scientific advances regarding its different phenotypes, leading to a more precise diagnosis and treatment with a multidisciplinary approach. In recent years, many paradigms around this pathology have changed, both in its aetiopathogenesis and in its diagnosis and treatment. In addition, previously forgotten aspects such as the relationship with obstetric complications and the associated comorbidities have taken on increasing interest. We discuss its impact throughout the patient's life, emphasizing new perspectives that are revolutionizing the way we understand endometriosis.

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Condition tags

endometriosisinfertility

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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