Approach to the Patient With Suspected Endometriosis
Endometriosis is defined by endometrial-like tissue outside the uterus, potentially caused by retrograde menstruation, vascular spread, implantation, metaplasia, genetics, or immunology.
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This chapter reviews endometriosis as tissue similar to normal endometrium located outside the endometrial cavity and myometrium, and discusses putative causes including retrograde menstruation, vascular or lymphatic dissemination, direct implantation, and metaplasia, possibly alongside genetic predisposition and immunologic disturbances. It provides a conceptual framework for approaching the patient with suspected endometriosis, outlining the uncertainty around etiology. The main limitation is that the cause of endometriosis is not clearly established, so the chapter emphasizes hypotheses rather than definitive mechanisms. This paper is centrally about endometriosis — it focuses on the approach to patients with suspected endometriosis and summarizes leading proposed etiologies and contributing factors.
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Cited by (1)
- Endometriosis 1995
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00