A prospective comparison of transvaginal ultrasonography and diagnostic hysteroscopy in the evaluation of patients with abnormal uterine bleeding: clinical implications
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This study prospectively compared transvaginal ultrasonography and diagnostic hysteroscopy for evaluating abnormal uterine bleeding, assessing their clinical implications.
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Abstract
OBJECTIVE: We determined the diagnostic value of transvaginal ultrasonography for endometrial and intrauterine abnormalities in patients with abnormal uterine bleeding.
STUDY DESIGN: Between June 1, 1992, and June 1, 1993, 279 consecutive patients underwent transvaginal ultrasonography. Findings were compared with the final diagnosis established by diagnostic hysteroscopy and histologic examination.
RESULTS: Transvaginal ultrasonography demonstrated a sensitivity of 0.96 and a specificity of 0.89. With a pretest probability (prevalence) of 0.42, this resulted in posttest probabilities of 0.03 in the case of a normal sonogram and 0.87 for an abnormal sonogram. The corresponding likelihood ratios were 0.04 and 9.09, respectively.
CONCLUSION: Transvaginal ultrasonography seems to be an effective procedure to exclude endometrial and intrauterine abnormalities. Its use could be implemented as a routine first-step procedure in patients with abnormal uterine bleeding, and it selects those in need of further diagnostic evaluation in the case of an abnormal or inconclusive sonogram.
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Cited by (9)
- Three-dimensional saline infusion sonography compared to two-dimensional saline infusion sonography for the diagnosis of focal intracavitary lesions 2017
- Premenopausal abnormal uterine bleeding and risk of endometrial cancer 2016
- Female Fertility Assessment 2012
- Gynecologic effects of arzoxifene in postmenopausal women with osteoporosis or low bone mass 2011
- A Cost Utility Analysis of Sonograhestrography Compared with Hysteroscopic Evaluation for Dysfunctional Uterine Bleeding 2000
- Radiographic imaging techniques for the diagnosis of abnormal uterine bleeding 2000
- Abnormal uterine bleeding in the reproductive years. Part I--pathogenesis and clinical investigation 1999
- Differential diagnosis of abnormal uterine bleeding 1996
- Office hysteroscopy versus transvaginal ultrasonography in the evaluation of patients with excessive uterine bleeding 1996
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- last seen: 2026-05-11T06:17:40.080092+00:00
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- last seen: 2026-10-08T21:59:07.256998+00:00
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