Further experience with norethynodrel in treatment of endometriosis.
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Abstract
A study involving 156 cases of endometriosis treated with norethynodrel (Enovid) was presented. Diagnosis was established by laparotomy culdoscopy culdoscopy followed by laparotomy or colpotomy. 132 cases were reevaluated following therapy. Complete regression was observed in 72% while an additional 18.2% were at least partially improved. Therapy was of no benefit in less than 9%. The majority of patients were reevaluated after 6 months by culdoscopy and therapy was discontinued. 14 patients were treated for an additional 3-9 months. The average duration of therapy was 6.7 months. Results with therapy following conservative operation were encouraging. Of 9 patients followed to date 8 had been relieved of their symptoms and 6 of these have had repeat culdoscopy with complete regression documented. 2 of these patients became pregnant. In patients who originally showed complete regression and in whom the follow-up had been for 6 months or longer recurrences developed in 11.8%. All patients experienced the side effects of weight gain abdominal fullness and breast enlargement and tenderness. Nausea was uncommon.
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Cited by (20)
- Classification of Endometriosis 2014
- Endometriosis: Disease Classification and Behavior 2011
- Laparoscopy for Diagnosis and Treatment of Endometriosis 2011
- Medical management of endometriosis and infertility 2000
- An Update on the Classification of Endometriosis 1999
- CLASSIFICATION OF ENDOMETRIOSIS 1997
- Classification and Staging of Endometriosis 1995
- Changing concepts of medical treatment of endometriosis 1993
- 6 Classification of endometriosis 1993
- Gestogens and anti-gestogens as treatment of endometriosis 1991
- The classification of endometriosis: A comprehensive review 1991
- Hormonal Therapy of Endometriosis 1989
- Classification of Endometriosis 1989
- Endometriosis 1984
- Endometriosis Presenting as Acute Appendicitis 1978
- Reoperation after initial treatment of endometriosis with conservative surgery 1978
- Conservative Treatment of Endometriosis: The Effects of Limited Surgery and Hormonal Pseudopregnancy 1976
- The prevention, inhibition, palliation, and treatment of endometriosis 1975
- Management of Endometriosis in the Infertile Patient 1975
- Endometriosis [ <i>Abridged</i> ] 1968
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- pubmed
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