Endometriosis and Ovarian Cancer

In: SpringerBriefs in Reproductive Biology · 2015 · pp. 61–74 · doi:10.1007/978-3-319-18308-4_7 · W2279383308
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Women with endometriosis have a higher risk of developing Type 1 ovarian cancers, specifically clear cell carcinoma and endometrioid adenocarcinoma, which are termed endometriosis-associated ovarian cancer.

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Abstract

Recent studies have provided much evidence to support the theory that endometriosis is actually a neoplasm and that affected cells can undergo malignant change. Women with endometriosis have a higher risk of certain types of ovarian cancer than the general female population [1]. Approximately 2.5 % of ovarian endometriosis turns malignant, but this may be an underestimation [2]. Studies have shown that Type 1 ovarian cancers such as clear cell carcinoma (CCC) and endometrioid adenocarcinoma (EAC) are associated with endometriosis [3]. Together, these carcinomas have been termed endometriosis-associated ovarian cancer (EAOC). The prevalence of endometriosis in ovarian cancer includes 39 % for clear cell carcinoma, 21 % for endometrioid carcinoma, and 3 % for serous and mucinous carcinoma [4]. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

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Keywords

- Ovarian Cancer - Malignant Transformation - Clear Cell Carcinoma - Human Epididymis Protein - Endometrioid Adenocarcinoma These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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