Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)

E H Johnson, Eugene H. Johnson, S E Morgenstern, Susan E. Morgenstern, Jill M. Perham, J M Perham, Stephen W. Barthold, S W Barthold
Journal of medical primatology · 1996 · vol. 25(6) , pp. 435–438 · doi:10.1111/j.1600-0684.1996.tb00040.x · PMID:9210029 · W1998031182
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

A 34-year-old female rhesus macaque spontaneously developed a colonic adenocarcinoma and endometriosis, presenting with partial colon obstruction and elevated CA 125 levels.

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Abstract

A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Colonic Neoplasms Primate Diseases Adenocarcinoma Adenocarcinoma Adenocarcinoma Animals Carcinoembryonic Antigen Carcinoembryonic Antigen Colonic Neoplasms Colonic Neoplasms Colonic Neoplasms Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (21)

Source provenance

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