The impact of bone loss in women with endometriosis

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

Premenopausal hypoestrogenism, seen with GnRH agonist therapy for endometriosis, is associated with bone density loss and increased future osteoporosis risk.

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Abstract

Low peak adult bone mass in a premenopausal woman puts her at increased risk for osteoporosis postmenopausally. Episodes of hypo-estrogenism premenopausally are associated with loss of bone density. This is seen with gonadotropin-releasing hormone agonist therapy for endometriosis, and thus prolonged or repeated courses of such treatment may increase the future risk of osteoporosis. Danazol and related compounds do not result in any bone loss but may have certain metabolic disadvantages.

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Condition tags

endometriosis

MeSH descriptors

Bone Density Danazol Endometriosis Gonadotropin-Releasing Hormone Osteoporosis Adult Adult Bone Density Bone Density Bone Density Danazol Danazol Endometriosis Endometriosis Estrogens Estrogens Estrogens Female Female Gonadotropin-Releasing Hormone

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (24)

Cited by (3)

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europepmc
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