Bone Mineral Density of the Lumbar Spine in Endometriosis Subjects Compared to an Age-Similar Control Population*
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Lumbar spine bone mineral density was not significantly different between women with endometriosis and age-similar controls, with both groups exhibiting normal BMD.
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Abstract
The purpose of this study was to compare the lumbar bone mineral density (BMD) between women with endometriosis and age-similar controls. Eighty-five women from nine North American centers (mean age, 30.7 yr) with laparoscopically proven endometriosis (study patients) were enrolled in a study of the efficacy of nafarelin, a GnRH agonist. Fifty-two women (mean age, 32 yr) from the Palo Alto area, with regular menstrual cycles and no major medical problems, served as age-similar controls. Both groups were predominantly (>92%) white. The mean BMD of the lumbar spine was 1.1 g/cm2 in both the study subjects and the controls. Study patients were 104.8% and controls were 104.8% of normal values for age. BMD was not significantly different in the two groups. BMD was not correlated with severity or time from diagnosis of endometriosis. BMD was positively correlated with weight (r = 0.28; P < 0.05) in both groups, with height (r = 0.30; P < 0.01) in study patients, and marginally with height (r = 0 26; P < 0.07) in controls. This study showed no difference in BMD between endometriosis patients and age-similar controls; both groups had normal BMD.
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Cited by (10)
- Bone mineral density in women with deep infiltrating endometriosis who have undergone early bilateral oophorectomy 2020
- The effects of a 3-month depot preparation of leuprorelin acetate on pain symptoms, bone mineral density and hormone levels in women with endometriosis—preliminary data analysis 2004
- Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density 2003
- Bone Remodeling and Structure in Postmenopausal Women Treated with Long-Term, High-Dose Estrogen Therapy 1999
- Effects of Add-Back Therapy on Bone Mineral Density and Pyridinium Crosslinks in Patients with Endometriosis Treated with Gonadotropin-Releasing Hormone Agonists 1999
- Women of Reproductive Age with Endometriosis are Not Osteopenic 1998
- Spontaneous reversibility of bone loss induced by gonadotropin-releasing hormone analog treatment. 1996
- Spontaneous reversibility of bone loss induced by gonadotropin-releasing hormone analog treatment 1996
- The impact of bone loss in women with endometriosis 1995
- Bone loss during gonadotropin releasing hormone agonist treatment and use of nasal calcitonin 1995
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- europepmc
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- openalex
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