Women of Reproductive Age with Endometriosis are Not Osteopenic
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This paper investigated bone mineral density in women of reproductive age with endometriosis and found no evidence of osteopenia.
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Abstract
ObjectiveTo determine whether women of reproductive age with endometriosis are osteopenic and whether bone density decreases with higher stages of endometriosis.DesignA multicenter cross-sectional study was performed.SettingThirty-nine gynecological clinics in the United States, Canada, and Puerto Rico.Patient(s)Two hundred forty-one women of reproductive age with laparoscopically proved endometriosis.Intervention(s)Diagnostic laparoscopy, bone densitometry.Main outcome measure(s)Endometriosis stages according to the criteria of the American Society for Reproductive Medicine, lumbar spine bone mineral density (L2-L4) as measured by dual-energy x-ray absorptiometry.Result(s)The mean lumbar spine bone mineral density, as well as the distribution of bone mineral density, of the women with endometriosis was similar to that of a normal population. There were no significant differences between endometriosis stage groups I-IV regarding bone mineral density as well as body weight, body mass index, and height.Conclusion(s)Women of reproductive age with endometriosis are not osteopenic. More advanced stages of endometriosis are not associated with a decrease in lumbar spine bone mineral density.
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Cited by (4)
- Bone mineral density in women with deep infiltrating endometriosis who have undergone early bilateral oophorectomy 2020
- Clinical Aspects of Endometriosis 2010
- Long-term fracture risk among women with proven endometriosis 2006
- The effects of a 3-month depot preparation of leuprorelin acetate on pain symptoms, bone mineral density and hormone levels in women with endometriosis—preliminary data analysis 2004
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- europepmc
- last seen: 2026-08-01T06:07:04.264727+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:40.754221+00:00
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