The impact of bone loss in women with endometriosis

J C Stevenson, John C. Stevenson
International Journal of Gynecology & Obstetrics · 1995 · vol. 50(S1) , pp. S11–5 · doi:10.1016/0020-7292(95)02509-b · PMID:8529769 · W2053624084
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

Premenopausal hypoestrogenism, seen with GnRH agonist therapy for endometriosis, is associated with bone density loss and increased future osteoporosis risk.

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Abstract

Low peak adult bone mass in a premenopausal woman puts her at increased risk for osteoporosis postmenopausally. Episodes of hypo-estrogenism premenopausally are associated with loss of bone density. This is seen with gonadotropin-releasing hormone agonist therapy for endometriosis, and thus prolonged or repeated courses of such treatment may increase the future risk of osteoporosis. Danazol and related compounds do not result in any bone loss but may have certain metabolic disadvantages.

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Condition tags

endometriosis

MeSH descriptors

Bone Density Danazol Endometriosis Gonadotropin-Releasing Hormone Osteoporosis Adult Bone Density Bone Density Danazol Endometriosis Estrogens Estrogens Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Osteoporosis Osteoporosis Premenopause

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

Cited by (3)

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