Changes in body composition with danazol therapy

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AI-generated summary by claude@2026-06, 2026-06-12

This paper investigated the effects of danazol therapy on body composition in patients.

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Abstract

Whole body lean and fat mass measurements by dual energy x-ray absorptiometry were performed in 14 premenopausal women undergoing danazol treatment for endometriosis. After 6 months, there was a significant increase in lean tissue mass. Body fat decreased but this was significantly less in the android (upper body segment) region than in the gynoid (lower body segment) region. Danazol thus has both anabolic and androgenic effects on body composition. Dual energy x-ray absorptiometry provides a new, noninvasive, and rapid means of studying body composition.

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Condition tags

endometriosis

MeSH descriptors

Body Composition Danazol Endometriosis Adipose Tissue Adipose Tissue Adult Anthropometry Anthropometry Body Composition Body Mass Index Body Weight Body Weight Danazol Diagnosis, Computer-Assisted Endometriosis Female Humans

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References (4)

Cited by (2)

Source provenance

europepmc
last seen: 2026-08-01T06:07:04.264727+00:00
openalex
last seen: 2026-05-13T18:37:28.025090+00:00
pubmed
last seen: 2026-05-13T22:11:54.876058+00:00
License: CC0 · commercial use OK