Correlation of CA-125 with different stages of endometriosis

Runa Laila, Nasrin Begum, Shayela Shamim, Md Mozammel Hoque
In: Bangabandhu Sheikh Mujib Medical University Journal · 2018 · vol. 11(1) , pp. 41–44 · doi:10.3329/bsmmuj.v11i1.35807 · W2793892040
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This study found a significant positive correlation between serum CA-125 levels and the stage of pelvic endometriosis in 70 diagnosed patients.

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Abstract

This study was conducted to evaluate the association of serum cancer antigen (CA-125) level with the severity of pelvic endometriosis. Seventy diagnosed cases of pelvic endometriosis were included in this study. The CA-125 level was estimated in all these patients, cutoff value of the serum CA-125 level was considered 35.0 U/mL. The correlations between serum CA-125 and different stages of endometriosis were evaluated by linear regression analysis. In Stage I of endometriosis, the mean serum CA-125 level was 21.8 ± 15.1 U/mL, in Stage II 26.0 ± 17.3 U/mL, in Stage III 83.2 ± 48.9 U/mL and in Stage IV 117.0 ± 41.6 U/mL. A significant positive correlation (r=0.729; p=0.001) was found between the serum CA-125 and different stages of endometriosis.
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Correlation of CA-125 with different stages of endometriosis DOI: https://doi.org/10.3329/bsmmuj.v11i1.35807Keywords: CA-125, EndometrosisAbstract This study was conducted to evaluate the association of serum cancer antigen (CA-125) level with the severity of pelvic endometriosis. Seventy diagnosed cases of pelvic endometriosis were included in this study. The CA-125 level was estimated in all these patients, cutoff value of the serum CA-125 level was considered 35.0 U/mL. The correlations between serum CA-125 and different stages of endometriosis were evaluated by linear regression analysis. In Stage I of endometriosis, the mean serum CA-125 level was 21.8 ± 15.1 U/mL, in Stage II 26.0 ± 17.3 U/mL, in Stage III 83.2 ± 48.9 U/mL and in Stage IV 117.0 ± 41.6 U/mL. A significant positive correlation (r=0.729; p=0.001) was found between the serum CA-125 and different stages of endometriosis. Downloads 270 326 Read 774 Additional Files Published How to Cite Issue Section License Copyright (c) 2018 Runa Laila, Begum Nasrin, Shayela Shamim, Md. Mozammel Hoque This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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endometriosis

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