Clinicopathologic characteristics of uterine adenomyoma in pregnant women

Jianhua Wang, Xiaohong He, Ruijin Wu, Xiangrong Xu
In: Fertility and Sterility · 2007 · vol. 88(1) , pp. 172–175 · doi:10.1016/j.fertnstert.2006.11.083 · PMID:17336979 · W2078930465
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This study investigated the clinicopathologic features of uterine adenomyoma in pregnant women, focusing on its presentation and characteristics during pregnancy.

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Abstract

ObjectiveTo study the clinicopathologic characteristics and the treatment means of pregnant women with uterine adenomyoma.DesignRetrospective, consecutive, controlled study.SettingUniversity hospital for obstetrics and gynecology.Patient(s)Eighteen pregnant women with uterine adenomyoma.Intervention(s)Data collection and statistical analysis.Main outcome measure(s)Eighteen pregnant women with uterine adenomyoma were diagnosed by excision of adenomyoma tissue during cesarean section and histopathology. The 18 subjects were retrospectively divided into treatment group (achieving this pregnancy by treatment; 10 cases) and control group (having no difficulty conceiving; 8 cases). The clinicopathologic characteristics and treatment means of the patients were analyzed retrospectively.Result(s)The mean volume of uterine adenomyoma in the treatment group was larger than that of the control group. The methods of treating women with uterine adenomyoma-associated infertility include GnRH agonist (GnRH-a: 6 cases), GnRH-a and IVF and embryo transfer (3 cases), and traditional Chinese medicines (1 case).Conclusion(s)Severe uterine adenomyoma correlate with infertility in women of childbearing age. GnRH-a is effective in treating women with uterine adenomyoma-associated infertility.

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