Endométriose : physiopathologie, facteurs génétiques et diagnostic clinique
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This paper reviews the pathophysiology, genetic factors, and clinical diagnosis of endometriosis.
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Abstract
Endometriosis is a multifactorial pathology. Trans-tubal reflux theory remains valid. Genetic and epigenetic factors associated with immunological perturbations are involved. The role of endocrine disruptors is discussed although epidemiological studies are contradictory. Therapeutics are primarily based on hormonal treatments but better understanding of pathophysiology should allow targeted non-hormonal therapy. The clinical examination is sometimes negative, which should not eliminate the diagnosis and imposes complementary examinations as best as possible by referents.
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Cited by (8)
- Voiding dysfunction after surgery for colorectal deep infiltrating endometriosis: an updated systematic review and meta-analysis 2025
- Diagnosis and treatment of tubal endometriosis in women undergoing laparoscopy: A case series from a single hospital 2022
- Genital endometriosis and fertility 2022
- Endometriosis: A Disease with Few Direct Treatment Options 2022
- Genetic, Epigenetic, and Steroidogenic Modulation Mechanisms in Endometriosis 2020
- The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing 2020
- The Effects of Leukocyte- and Platelet-Rich Plasma (L-Prp) and Pure Platelet-Rich Plasma (P-Prp) an a Rat Endometriosis Model 2019
- Pathogenomics of Endometriosis Development 2018
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