Endometriosis

Sara Clemenza, Dante Campana, Silvia Vannuccini, Larissa Milani Coutinho, Felice Petraglia
In: Endocrinology · 2020 · pp. 1–17 · doi:10.1007/978-3-030-03594-5_8-1 · W4251255179
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-09 ⓘ

Endometriosis is a chronic benign disease affecting 6-10% of women, characterized by endometrial tissue outside the uterus, causing pain and infertility.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

The paper provides an overview of endometriosis as a chronic benign condition characterized by ectopic endometrial tissue, affecting about 6–10% of women, typically during reproductive years and associated with pain and infertility. It reviews major proposed pathogenesis mechanisms (retrograde menstruation, blood/lymphatic dissemination, and metaplasia or stem-cell origins) and describes downstream tissue effects including inflammation, angiogenesis, adhesions, fibrosis, scarring, neuronal infiltration, and anatomical distortion. It outlines how endometriosis is clinically classified (superficial/peritoneal, ovarian, and deep disease) and notes that diagnosis relies on history and pelvic examination supported by imaging, particularly transvaginal ultrasound as a first approach, while also stating that the condition requires lifelong management, aiming to use medical therapy and avoid repeated surgeries. The paper does not explicitly state study limitations but is a narrative reference-style synthesis. This paper is centrally about endometriosis — it reviews endometriosis definitions, pathogenesis theories, clinical features, classification, and diagnostic/management frameworks.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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