Larissa Milani Coutinho
ORCID: 0000-0002-7297-5216
· 8 papers in corpus
article
2024
• Endometriosis is fueled by local estradiol accumulation that might be due to deficient HSD17B2 activity. • The microRNAs miR-124-3p and miR-26b-5p target the HSD17B2 gene. • This study measured miR-124-3p and miR-26b-5p in endometriotic l…
dissertation
2021
Expressão da 17β-hidroxiesteroide desidrogenase tipo 2 (17βHSD2) na endometriose: novas perspectivas
Background: Endometriosis is an estrogen-dependent disease. A theory of deficient 17βHSD2 expression in lesions, but not in paired eutopic endometrium, leading to high levels of local estradiol has been described as a potential molecular me…
book-chapter
2020
book-chapter
2020
article
2020
review
2020
BACKGROUND: Despite intense research, it remains intriguing why hormonal therapies in general and progestins in particular sometimes fail in endometriosis. OBJECTIVE AND RATIONALE: We review here the action mechanisms of progesterone recept…
review
2019
Endometriosis is a benign gynecological disorder which presents significant challenges in terms of diagnosis and management. Despite decades of research, there are no sufficiently sensitive and specific signs and symptoms nor blood tests fo…
article
2019
The present study investigated the effect of surgical treatment of endometriosis on physical and mental health. We undertook a prospective survey including 153 premenopausal women with histological diagnosis of endometriosis. The Short Form…