The effect of ibuprofen on the intrauterine pressure and menstrual pain of dysmenorrheic patients
Non-randomised trial
OA: closed
CC0
⤵ 10 in-corpus citations
AI-generated summary
This study investigated how ibuprofen affects intrauterine pressure and menstrual pain in patients experiencing dysmenorrhea.
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Abstract
In 12 dysmenorrheic patients we examined the therapeutic action of the Prostaglandin-synthesis inhibitor: Ibuprofen, a non-steroidal analgesic agent. Ibuprofen highly significantly reduced the resting pressure (P less than 0.001), active pressure (P less than 0.001) and frequency (P less than 0.05) of cyclic activity of the uterus, as well as menstrual pain (P less than 0.001). Since these effects occurred after a single oral dose of 800 mg Ibuprofen, without side effects or complications, extensive field trials are recommended with this and other PG-synthesis inhibitors, to assess their therapeutic benefits.
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References (10)
- The effect of naproxen-sodium on the intrauterine pressure and menstrual pain of dysmenorrheic patients via openalex
- The effect of naproxen-sodium on the prostaglandin concentrations of the menstrual blood and uterine "jet-washings" in dysmenorrheic women via openalex
- W2029602174 via openalex
- W2054393602 via openalex
- W2076763552 via openalex
- W2405175138 via openalex
- W2470237574 via openalex
- W1991914374 via openalex
- W4300049346 via openalex
- W2002297781 via openalex
Cited by (9)
- Thermachoice endometrial ablation in the outpatient setting, without local anesthesia or intravenous sedation: a prospective cohort study 2005
- Prostaglandins in Dysmenorrhoea and Endometriosis 1992
- An Objective Evaluation of Flurbiprofen and Tranexamic Acid in the Treatment of Idiopathic Menorrhagia 1988
- Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed 1984
- Ibuprofen and dysmenorrhea 1984
- Ibuprofen and dysmenorrhea 1984
- Distribution analysis of intrauterine pressure in nonpregnant dysmenorrheic women 1984
- Prostaglandin secretion by human endometrium in vitro 1982
- Presence of gap junctions in the myometrium of women during various stages of menstruation 1980
SciLite annotations
chemicals 5
ibuprofen
prostaglandin
ibuprofen
ibuprofen
ibuprofen
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:35:58.313463+00:00
- scilite
- last seen: 2026-05-18T04:57:49.680383+00:00
- unpaywall
- last seen: 2026-10-13T06:25:51.201866+00:00
License: CC0
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