The correlation between Anogenital Distance (AGD) and Endometriosis

Ricky Ricardo Nalley, Nusratuddin Abdullah, Fatmawati Madya, St. Nur Asni, Sriwijaya Sriwijaya, Susiawaty Susiawaty
In: Bali Medical Journal · 2023 · vol. 12(3) , pp. 2975–2980 · doi:10.15562/bmj.v12i3.4707 · W4392842102
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found that Anogenital Distance to the Anus and Fundiform ligament (AGD-AF) length is significantly shorter in endometriosis patients compared to controls, suggesting its potential as a diagnostic predictor.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text ⓘ

This paper investigates the correlation between anogenital distance (AGD) and endometriosis, focusing on whether AGD measurements are associated with the presence of endometriosis. Using a clinical research approach (as indicated by the obstetrics and gynecology affiliations and the study’s correlation framing), it analyzes AGD as a variable in relation to endometriosis status. The key finding reported is the presence or absence of an observed correlation between AGD and endometriosis, with any limitation arising from the study design and measurement context (as typical for correlation studies is the paper’s stated constraint). This paper is centrally about endometriosis — it examines the relationship between anogenital distance and endometriosis.

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Abstract

Link of Video Abstract: https://youtu.be/XmIf_eavZto Background: Endometriosis is a disease that causes recurrent chronic pain related to menstruation in around 10% of women of reproductive age. However, current non-invasive diagnostic tools are not sufficiently good at detecting endometriosis. Anogenital Distance (AGD) is a new measurement parameter that is non-invasive and proven to be used to help detect endometriosis. This study aims to assess the ability of AGD in detecting endometriosis. Methods: This study is a diagnostic test study involving 35 endometriosis patients and 35 controls by comparing the clinical characteristics of the patients and the length of AGD-AF and AGD-AC for both groups. Data were analyzed using SPSS version 22.0 for Windows. Results: The median AGD-AF length in endometriosis patients and controls were 22.65 + 6.54 and 29.53 + 3.52 (p<0.001) respectively, with AGD-AC lengths being 68.04 + 5.8 and 66.81 + 5.49 (p=0.369). In the multivariate logistic regression test, AGD-AF length was a single significant predictor (p <0.001). Based on the ROC curve, the length of AGD-AF with a cut-off of 23.35 mm has a sensitivity and specificity value of 97.1% and 65.7%. Conclusion: This study states that there is a correlation between AGD and endometriosis, especially AGD-AF, so it can be used as one of the predictors to help detect endometriosis.
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The correlation between Anogenital Distance (AGD) and Endometriosis - Ricky Ricardo Nalley , - Nusratuddin Abdullah , - Fatmawati Madya , - St. Nur Asni , - Sriwijaya , - Susiawaty , Ricky Ricardo Nalley Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Search for the other articles from the author in: Google Scholar | PubMed | BMJ Journal Nusratuddin Abdullah Fertility and Reproductive Endocrinology Subdivision, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Search for the other articles from the author in: Google Scholar | PubMed | BMJ Journal Fatmawati Madya Fertility and Reproductive Endocrinology Subdivision, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Search for the other articles from the author in: Google Scholar | PubMed | BMJ Journal St. Nur Asni Urogynecology and Reconstructive Pelvic Surgery Subdivision, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Search for the other articles from the author in: Google Scholar | PubMed | BMJ Journal Sriwijaya Fertility and Reproductive Endocrinology Subdivision, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Search for the other articles from the author in: Google Scholar | PubMed | BMJ Journal Susiawaty Social Obstetrics and Gynecology Subdivision, Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Search for the other articles from the author in: Google Scholar | PubMed | BMJ Journal - pdf | - DOI: https://doi.org/10.15562/bmj.v12i3.4707 | - Published: 2023-10-07

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