Fluorescent detection of rabbit endometrial implants resulting from monodispersed viable cell suspensions
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Researchers developed a fluorescent method to detect rabbit endometrial implants created from injected suspensions of viable endometrial cells.
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Abstract
A model for early stage endometriosis was prepared in rabbits by intraperitoneal injection of monodispersed viable endometrial cells. With this model, we have found that DHE fluorescence increases the sensitivity of detection of endometrial tissue. The potential experimental and clinical significance of ectopic endometrial detection by porphyrin fluorescence is enhanced by the recent report of endometrial transplant destruction by PDT. Although caution must be exercised for extrapolation from animal experiments to human conditions, these results encourage further evaluation of photosensitization for the study and potential treatment of disorders involving endometrial tissue.
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References (6)
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Cited by (9)
- Increased Expression Levels of Metalloprotease, Tissue Inhibitor of Metalloprotease, Metallothionein, and p63 in Ectopic Endometrium: An Animal Experimental Study 2018
- Avaliação de marcadores de proliferação celular e apoptose em tecido endometrial eutópico e ectópico em modelo experimental de endometriose em coelhas 2007
- Endometriosis: harmful survival of an ectopic tissue 2006
- Development of an experimental model of endometriosis in rabbits 2004
- Modelo experimental para endometriose em coelhas com seguimento evolutivo das lesões 2004
- Was Sampson wrong? 2002
- Role of endocrine status and cell type in adhesion of human endometrial cells to the peritoneum in nude mice 2002
- Fluorescence diagnosis of endometriosis on the chorioallantoic membrane using 5-aminolaevulinic acid 2000
- Photodynamic Therapy in Gynaecology: Bringing Scientific Discovery to the Clinical Arena 1997
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