Cutaneous decidualized endometriosis in a nonpregnant female: a potential pseudomalignancy

Brittney DeClerck, Brittney K DeClerck, DeClerck BK, Miriam D. Post, Post MD, Wisell JA, Joshua A Wisell, J. Wisell
The American Journal of dermatopathology · 2012 · vol. 34(5) , pp. 541–543 · doi:10.1097/dad.0b013e3182473172 · PMID:22534633 · W2014192206
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This paper presents a case of decidualized cutaneous endometriosis in a nonpregnant female, reviewing its histopathologic and immunohistochemical features and the relevant literature.

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Abstract

Endometriosis is a disease process characterized by ectopic endometrial tissue. Involvement most commonly occurs in the lower pelvis, outside the uterine cavity, but can occur elsewhere, including the skin. Cutaneous endometriosis is a rare manifestation of this disease, with decidualization occurring in a very small minority of cases, almost always seen in pregnant females. Cutaneous involvement of endometriosis may present a diagnostic problem for the pathologist, particularly in the event of decidualization. Decidualization may mimic a malignancy and as a result may result in unnecessary diagnostic studies for the patient. We present a case of a nonpregnant patient with decidualized cutaneous endometriosis, discuss the histopathologic and immunohistochemical features of this entity, and review the pertinent literature on this subject. To our knowledge, this is the second reported case of cutaneous decidualized endometriosis in a nonpregnant female.

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Condition tags

endometriosis

MeSH descriptors

Cesarean Section Cicatrix Decidua Diagnostic Errors Endometriosis Skin Diseases Skin Neoplasms Adult Adult Biopsy Biopsy Cesarean Section Cesarean Section Cicatrix Cicatrix Cicatrix Cicatrix Cicatrix Decidua Decidua

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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