Deep dyspareunia and central sensitization in endometriosis: A prospective study with online daily pain diary

Natasha L. Orr; Michelle Lisonek; Heather Noga; Catherine Allaire; Manon Allaire; Mohamed A. Bedaiwy; Sarka Lisonkova; Kelly B. Smith; Paul J. Yong

doi:10.1016/j.jeud.2025.100132

Deep dyspareunia and central sensitization in endometriosis: A prospective study with online daily pain diary

Natasha L. Orr, Michelle Lisonek, Heather Noga, Catherine Allaire, Manon Allaire, Mohamed A. Bedaiwy, Sarka Lisonkova, Kelly B. Smith, Paul J. Yong

In: Journal of Endometriosis and Uterine Disorders · 2025 · vol. 12 , pp. 100132 · doi:10.1016/j.jeud.2025.100132 · W4413110015

OA: diamond CC0

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study investigated the relationship between deep dyspareunia, central sensitization, and daily pain patterns in individuals with endometriosis using an online pain diary.

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Condition tags

endometriosisdyspareunia

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (57)

Anatomic Sites and Associated Clinical Factors for Deep Dyspareunia via openalex
Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients via openalex
Association of Central Sensitization Inventory Scores With Pain Outcomes After Endometriosis Surgery via openalex
Bladder base tenderness in the etiology of deep dyspareunia via openalex
Central changes associated with chronic pelvic pain and endometriosis via openalex
Central sensitization inventory in endometriosis via openalex
Deep Dyspareunia and Sexual Quality of Life in Women With Endometriosis via openalex
Deep Dyspareunia in Endometriosis: A Proposed Framework Based on Pain Mechanisms and Genito-Pelvic Pain Penetration Disorder via openalex
Deep Dyspareunia in Endometriosis: Role of the Bladder and Pelvic Floor via openalex
Deep Dyspareunia: Review of Pathophysiology and Proposed Future Research Priorities via openalex
Deep Dyspareunia, Superficial Dyspareunia, and Infertility Concerns Among Women With Endometriosis: A Cross-Sectional Study via openalex
Endometriosis and infertility: a review of the pathogenesis and treatment of endometriosis-associated infertility via openalex
Functional Connectivity is Associated With Altered Brain Chemistry in Women With Endometriosis-Associated Chronic Pelvic Pain via openalex
Impact of endometriosis on quality of life and mental health: pelvic pain makes the difference via openalex
Increased pressure pain sensitivity in women with endometriosis and chronic pelvic pain via openalex
Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk via openalex
Multifactorial contributors to the severity of chronic pelvic pain in women via openalex
Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain via openalex
Pelvic floor tenderness in the etiology of superficial dyspareunia via openalex
Phenotyping Sexual Pain in Endometriosis Using the Central Sensitization Inventory via openalex
Prospective Cohort of Deep Dyspareunia in an Interdisciplinary Setting via openalex
Reduced pain thresholds and signs of sensitization in women with persistent pelvic pain and suspected endometriosis via openalex
Reevaluating response and failure of medical treatment of endometriosis: a systematic review via openalex
Sprouted innervation into uterine transplants contributes to the development of hyperalgesia in a rat model of endometriosis via openalex
The burden of endometriosis symptoms on health-related quality of life in women in the United States: a cross-sectional study via openalex
The social and psychological impact of endometriosis on women's lives: a critical narrative review via openalex
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Cited by (1)

Integrating the Central Sensitization Inventory (CSI) into Neuropelveological Practice: A Systematic Review of Endometriosis and Overlapping Pelvic Pain Syndromes 2026

Source provenance

openalex: last seen: 2026-06-10T17:14:06.276822+00:00

License: CC0 · commercial use OK

[1] Anatomic Sites and Associated Clinical Factors for Deep Dyspareunia via openalex

[2] Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients via openalex

[3] Association of Central Sensitization Inventory Scores With Pain Outcomes After Endometriosis Surgery via openalex

[4] Bladder base tenderness in the etiology of deep dyspareunia via openalex

[5] Central changes associated with chronic pelvic pain and endometriosis via openalex

[6] Central sensitization inventory in endometriosis via openalex

[7] Deep Dyspareunia and Sexual Quality of Life in Women With Endometriosis via openalex

[8] Deep Dyspareunia in Endometriosis: A Proposed Framework Based on Pain Mechanisms and Genito-Pelvic Pain Penetration Disorder via openalex

[9] Deep Dyspareunia in Endometriosis: Role of the Bladder and Pelvic Floor via openalex

[10] Deep Dyspareunia: Review of Pathophysiology and Proposed Future Research Priorities via openalex

[11] Deep Dyspareunia, Superficial Dyspareunia, and Infertility Concerns Among Women With Endometriosis: A Cross-Sectional Study via openalex

[12] Endometriosis and infertility: a review of the pathogenesis and treatment of endometriosis-associated infertility via openalex

[13] Functional Connectivity is Associated With Altered Brain Chemistry in Women With Endometriosis-Associated Chronic Pelvic Pain via openalex

[14] Impact of endometriosis on quality of life and mental health: pelvic pain makes the difference via openalex

[15] Increased pressure pain sensitivity in women with endometriosis and chronic pelvic pain via openalex

[16] Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk via openalex

[17] Multifactorial contributors to the severity of chronic pelvic pain in women via openalex

[18] Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain via openalex

[19] Pelvic floor tenderness in the etiology of superficial dyspareunia via openalex

[20] Phenotyping Sexual Pain in Endometriosis Using the Central Sensitization Inventory via openalex

[21] Prospective Cohort of Deep Dyspareunia in an Interdisciplinary Setting via openalex

[22] Reduced pain thresholds and signs of sensitization in women with persistent pelvic pain and suspected endometriosis via openalex

[23] Reevaluating response and failure of medical treatment of endometriosis: a systematic review via openalex

[24] Sprouted innervation into uterine transplants contributes to the development of hyperalgesia in a rat model of endometriosis via openalex

[25] The burden of endometriosis symptoms on health-related quality of life in women in the United States: a cross-sectional study via openalex

[26] The social and psychological impact of endometriosis on women's lives: a critical narrative review via openalex

[27] W3184396469 via openalex

[28] W4234160457 via openalex

[29] W4379877235 via openalex

[30] W4380742848 via openalex

[31] W6600418809 via openalex

[32] W2766251233 via openalex

[33] W1889351252 via openalex

[34] W2004323875 via openalex

[35] W2017658725 via openalex

[36] W2024125959 via openalex

[37] W2043705607 via openalex

[38] W2049291748 via openalex

[39] W2064201279 via openalex

[40] W2064333636 via openalex

[41] W2066905678 via openalex

[42] W2085922363 via openalex

[43] W2089011195 via openalex

[44] W2097247989 via openalex

[45] W2132322340 via openalex

[46] W2133316133 via openalex

[47] W2155524482 via openalex

[48] W2157840151 via openalex

[49] W2160662805 via openalex

[50] W2291126069 via openalex

[51] W2295398547 via openalex

[52] W10400876 via openalex

[53] W2890354775 via openalex

[54] W2898908320 via openalex

[55] W3044976580 via openalex

[56] W3152283701 via openalex

[57] W3161747450 via openalex