Leukocytes: essential cells in ovarian function and ovulation

Published online by Cambridge University Press: 03 June 2009 The disciplines of reproduction and immunology, once quite discrete, are now closely associated, with compelling evidence to suggest that immune mechanisms play important roles in the cervix, uterus, fallopian tubes and ovary. Cells and mediators classically described as part of the immune system are found throughout the reproductive tract. Disorders of reproduction, including pre-eclampsia, unexplained infertility, endometriosis, recurrent miscarriage and disturbed fetal growth almost certainly have some of their origins in the dysfunction of immune regulation. There appears to be some evidence that immune disorders, such as rheumatoid arthritis and scleroderma, can manifest as infertility, before clinical disease becomes apparent. - Type - Research Article - Information - Copyright - Copyright © Cambridge University Press 1997 1Kelly, RW. Immunosuppressive mechanisms in semen: implications for contraception. 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